摘要
本试验先以大肠杆菌临床分离株复制小鼠细菌性腹泻模型,然后经口灌服1/20 LD_(50)(低剂量组)、1/10 LD_(50)(中剂量组)和1/5 LD_(50)(高剂量组)的巴天酸模水提物,观察其对大肠杆菌感染小鼠胃肠蠕动的影响。结果表明,巴天酸模低、中、高剂量组小鼠的肠推进率分别为35.72%、37.10%、48.25%;与腹泻模型组相比,高剂量组的肠推进率差异极显著,低剂量组和中剂量组差异显著。
To observe the effect of Rumex patientia L. water extraction on gastrointestinal motility induced by Escherichia coli in mice,the bacterial diarrhea model in mice was replicated by Escherichia coli clinical isolates,then 1/20 LD_（50）（low dose group）,1/10 LD_（50）（medium dose group） and 1/5 LD_（50）（high dose group） water extraction were administrated by oral administration in this study. The results showed that the small intestinal propulsive rate of the low dose group,the medium dose group and the high dose group were 35.72%、37.10%、48.25% respectively. Compared with the model group, the small intestinal propulsive rate of the high dose group had extremely significant difference,and the low dose group and medium dose group had significant difference.
作者
孙艳
黄志宏
陈朝喜
Sun Yan1, Huang Zhihong2, Chen Chaoxi2.(1.Institute of Animal and Veterinary Sciences,Liangshan Yi Autonomous Prefecture,Siehuan Xichang 615042; 2.College of Life Science and Technology,Southwest University for Nationalities,Sichuan Chengdu 610041 ,Chin)
出处
《四川畜牧兽医》
2018年第4期22-23,26,共3页
Sichuan Animal & Veterinary Sciences
基金
四川省科技培训计划项目(2016KZ0007)
凉山州科技计划项目(16YYJS0113)
西南民族大学中央高校基本科研业务费专项资金青年教师基金项目(2017NZYQN38)
关键词
巴天酸模
半数致死量
肠推进率
Rumex patientia L
LDso
Small intestinal propulsive rate
