摘要
目的了解双相障碍患者的临床特征、诊治情况,为双相障碍的诊疗提供参考。方法采用回顾性调查方法,对2015年12月-2017年6月在北京回龙观医院住院治疗的227例符合《精神障碍诊断与统计手册(第4版)》(DSM-IV)双相障碍诊断标准的患者进行资料收集,包括发病年龄、首次就诊年龄、发作次数、家族史等人口学资料以及既往诊断治疗等临床资料。结果双相障碍患者平均发病年龄(25.41±9.64)岁,首次就诊年龄(27.02±10.52)岁。抑郁发作、躁狂发作及混合发作三组患者的住院次数比较差异有统计学意义(χ2=15.78,P<0.01)。首次发病即就诊者疾病发作次数与首次发病后未就诊者比较差异无统计学意义(P>0.05)。而首次就诊于精神专科医院的患者在发病次数相对较少时便被确诊(P<0.01)。首次就诊于精神科专科医院的患者使用情感稳定剂的人数与首次就诊于非精神科专科医院者比较差异有统计学意义(χ2=60.00,P<0.01)。结论首次发病就诊于精神专科医院的患者应用情感稳定剂的人数较首次就诊于非精神专科医院多,且在发病次数较少时被确诊。
Objective To investigate the clinical characteristics and treatment in patients with bipolar disorder,and to provide references for the diagnosis and treatment of bipolar disorder. Methods 227 inpatients with disorder diagnosed with Diagnostic and Statistical Manual of Mental Disorders,fourth edition( DSM-IV) in Beijing Huilongguan Hospital from December 2015 to June 2017 were enrolled in the study. Retrospective investigation was used to collect the clinical information including age of onset,first visit age,number of attacks,family history,diagnosis,therapeutic effects and treatment. Results The average onset age of 227 patients with bipolar disorder was( 25. 41 ± 9. 64),and the age of first visit was( 27. 02 ± 10. 52). The difference between the 3 groups of the patients with manic episode,depressive episode and mixed attack was statistically significant( χ2= 15. 78,P < 0. 01). The numbers of hospital visit and hospitalization of mood disorders showed no significant difference for the patients who visited the hospital at the first attack( P > 0. 05). Patients who visited a psychiatric hospital at the first time of attack were with less episodes( P < 0. 01). The number of emotion stabilizers used in patients attending psychiatric hospitals and non-psychiatric hospitals for the first time had statistical significance( χ2= 60. 00,P < 0. 01). Conclusion The number of emotion stabilizers used in patients who visited psychiatric hospitals was higher than non-psychiatric hospitals,and in the incidence of less was diagnosed.
出处
《四川精神卫生》
2018年第1期36-39,共4页
Sichuan Mental Health
基金
首都卫生发展科研专项项目(2018-3-2132)
北京市属医院科研培育计划项目(PX2017070)
关键词
双相障碍
临床特征
情感稳定剂
首次就诊
发作次数
Bipolar disorder
Clinical characteristics
Mood stabilizer
First visit
Attack times
