摘要
目的:探讨ELISA联合TRUST检测在新生儿梅毒诊断中的应用价值。方法:回顾性分析78例梅毒产妇分娩的新生儿的临床资料,患儿均行ELISA和TRUST检测,并均经梅毒螺旋体明胶凝集试验(TPPA)确诊。比较ELISA联合TRUST和单项检测的准确度、敏感度与特异度;统计母婴垂直传播情况。结果:梅毒母婴垂直传播率为75.64%(59/78)。ELISA联合TRUST法的诊断准确度和敏感度均明显大于单项检测,差异有统计学意义(P<0.05)。结论:ELISA联合TRUST检测在新生儿梅毒诊断中具有较高的应用价值。
Objective: To analyze application value of ELISA combined with TRUST test in diagnosis of neonatal syphilis.Methods: The clinical data of 78 neonates,whose mothers were syphilis-infected patients,were retrospectively analyzed. All the cases were detected with enzyme linked immunosorbent assay( ELISA) and tolulized red unheated serum test( TRUST),and were confirmed by the Treponema pallidum test( TPPA). The accuracies,sensitivities and specificities of ELISA combined with TRUST and single test were compared. Further,the maternal-infant vertical transmission situations were statistically analyzed. Results: The maternal-infant vertical transmission rate of syphilis was 75.64%( 59/78). The accuracy and specificity of ELISA combined with TRUST were significantly higher than those of the single test,and the differences were statistical significance( P<0.05). Conclusions: ELISA combined with TRUST test has a high application value in the diagnosis of neonatal syphilis.
出处
《中国民康医学》
2018年第2期19-20,42,共3页
Medical Journal of Chinese People’s Health
