摘要
目的 研究血清电解质及尿比重、PH值与上尿路结石的相关性,初步探讨青年战士结石的发病相关因素.方法 回顾性分析201 1年3月至2014年3月因上尿路结石住院治疗的129例青年战士临床资料,另选192例青年战士健康体检资料作为对照,比较两者血清钾（K）、钠（Na）、氯（Cl）、钙（Ca）、二氧化碳结合力（CO2-CP）、尿比重（SG）和PH值的差异,并构建Logistic回归方程Y=exp（-128.67-1.91×K＋0.35 × Na ＋4.42×Ca-1.75 ×PH ＋82.89×SG）/[1＋exp（-128.67-1.91×K＋0.35×Na＋4.42×Ca-1.75×PH＋82.89×SG）].结果 与对照组相比,结石组血清钾和尿PH值明显偏低,而血清钠、钙和尿比重明显偏高.经过Lo-gistic回归后得到青年战士上尿路结石的风险方程.结论 血清钾、钠、钙、尿比重和PH值可能参与上尿路结石的发生过程.风险方程的应用有助于该疾病的个体化防治.
Objective To explore risk factors of upper urinary tract lithiasis in young soldiers by assessing the relevance among serum electrolyte,routine urine test and the development of lithiasis.Methods Between March 2011 and March 2014,a total of 129 young soldiers who suffered from upper urinary tract lithiasis were involved in this research.Other 192 health young soldiers were considered as control.Serum levels of K,Na,Cl,Ca,CO2-CP,and urine PH and urine specific gravity （SG） were analyzed between these two groups.Results There was significant difference in levels of serum K,Na,Ca,and urine PH.Logisitic regression analyse showed that K and urine PH were protective factors,while Na,Ca,and SG were risk factors for upper urinary tract lithiasis in young soldiers.The risk equation was established by Logistic regression.Y =exp（-128.67-1.91 × K ＋0.35 ×Na＋4.42×Ca-1.75×PH＋82.89×SG）/[1 ＋exp（-128.67-1.91 ×K＋0.35×Na＋4.42×Ca-1.75 × PH ＋ 82.89 × SG）] Conclusions Serum K,Na,Ca,and urine PH and SG may play role in pathogenesis of upper urinary tract lithiasis,and the use of risk equation may contribute to preventing and curing this disease with individualized pattern.
出处
《国际泌尿系统杂志》
2018年第1期92-95,共4页
International Journal of Urology and Nephrology
基金
解放军252医院院管课题基金资助项目（YY2012-12,252YY20110038）
关键词
尿路结石
军事人员
Urinary Calculi
Military Personnel
