摘要
目的探讨黛力新联合伊曲康唑治疗复发性真菌性阴道炎伴焦虑患者的临床疗效。方法将92例复发性真菌性阴道炎伴焦虑患者随机分为观察组与对照组,各46例。对照组予以伊曲康唑治疗,观察组在对照组基础上加用黛力新。比较两组临床疗效、复发率,治疗前后评价焦虑自评量表(SAS)和抑郁自评量表(SDS)评分。结果观察组的症状缓解时间较对照组明显缩短(P<0.05),观察组的治疗总有效率为97.83%,显著高于对照组的84.78%(P<0.05);治疗后两组SAS、SDS评分均显著降低,且观察组显著低于对照组(P<0.05);随访6个月,观察组复发率为4.76%,显著低于对照组的21.62%(P<0.05)。结论黛力新联合伊曲康唑能够促进复发性真菌性阴道炎伴焦虑患者临床症状与焦虑症状的缓解,降低复发率。
Objective To investigate the clinical efficacy of Deanxit combined with hraconazole in recurrent fungal vaginitis patients with anxiety. Methods Ninety-two recurrent fungal vaginitis patients with anxiety were randomly divided into observation group and control group, 46 cases in each group. The control group was treated with Itraconazole, while the observation group was treated with Deanxit on the basis of control group. The clinical efficacy and recurrence rate between the two groups were compared, the Self -rating Anxiety Scale （ SAS ） and Self - rating Depression Scale （ SDS ） scores were evaluated to all the patients before and after treatment. Results The remission time of the observation group was significantly shorter than that of the control group （ P 〈 0.05 ）; The total effective rate was 97.83 % in the observation group, which was significantly higher than 84.78 % in the control group （ P〈0.05 ）; After treatment, the SAS and SDS scores were significantly decreased in the two groups, and the scores in observation group were significantly lower than those in the control group （P 〈 0.05 ）; The recurrence rate was 4.76 % in the obser- vation group at 6 months after treatment, which was significantly lower than 21.62 % in the control group （ P 〈 0.05 ） . Conclusion Deanxit combined with Itraconazole can effectively alleviate the clinical symptoms and anxiety, reduce the recurrence rate of vaginitis in recurrent fungal vaginitis patients with anxiety.
出处
《国际精神病学杂志》
2018年第1期154-156,166,共4页
Journal Of International Psychiatry
