摘要
目的:观察臭氧水联合臭氧油治疗足癣的临床疗效和不良反应。方法:60例确诊为足癣的患者随机被分为对照组和臭氧组。对照组患者足癣用自来水清洗后用萘替芬酮康唑软膏外涂,每日1次;臭氧组患者足癣用臭氧水清洗后外涂臭氧油,每日1次;均治疗4周。在治疗第1,2和4周结束时,分别采集临床评分数据评价患者病情的改善情况;并在治疗前、治疗第4周末进行真菌镜检,评估真菌感染的情况。结果:治疗4周后,真菌镜检结果显示臭氧组1例阳性,对照组6例阳性,两组间真菌镜检阳性率比较差异无统计学意义(P>0.05)。第1,2,4周的临床评分比较显示不同时间点两组治疗效果差异无统计学意义(P>0.05)。结论:臭氧水联合臭氧油外用治疗足癣有效,且无不良反应。
Objective： To evaluate efficacy of combined therapy with ozonated water and oil on patients with tinea pedis. Methods： A total of 60 patients with tinea pedis were divided into 2 groups in a randomized and blinded test. Patients in a control group were treated with naftinfine hydrochloride and ketoconazole cream once a day. Patients in an ozone group were treated with ozonated water bath and then ozonated oil topical application once a dain Patients in the 2 groups were treated for 4 weeks. Clinical and laboratory data were collected for both groups at the end of the 1st week, the 2nd week, and the 4th week. The Pearson chi-square was performed to compare scores of the clinical signs and symptoms （CSS） and the mycological result between the 2 groups. Independent samples T-test was performed to compare the curative effect between the 2 groups. Results： After 4 weeks＇ treatment, 6 patients were positive in the control group determined by mycological examination while 1 patient was positive in the ozone group, with no significant difference between the 2 groups （P〉0.05）. Changes in CSS at the end of the 1st week, 2nd week, and 4th week were obtained and showed no significant difference between the 2 groups at the 3 different time points （P〉0.05）. No side effects were observed. Conclusion： Combination of ozonated water with shows no side effects. oil is effective on treatment oftinea pedis and it
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2018年第2期147-151,共5页
Journal of Central South University ：Medical Science
关键词
足癣
臭氧水
臭氧油
萘替芬酮康唑软膏
tinea pedis
ozonated water
ozonated oil
naftinfine hydrochloride and ketoconazole cream
