摘要
目的研究半夏泻心汤剂加减方治疗慢性结肠炎的疗效和安全性。方法在2013年1月—2016年12月来我院就诊的慢性结肠炎患者中选出98例随机分组,对照组患者给予西医治疗,观察组患者给予半夏泻心汤加减治疗,对比两组患者的治疗总有效率、实验室检验指标值、不良反应发生率等。结果观察组患者治疗2个月后的总有效率为95.92%,比对照组的79.59%更高,且不良反应发生率为6.12%,低于对照组的22.45%,P<0.05;治疗2个月时,观察组患者的IL-1、IL-8、TNF-α水平均明显低于对照组,且IL-10水平高于对照组,P<0.05。结论对慢性结肠炎患者应用半夏泻心汤加减方治疗效果确切,安全性高,有助于促进患者免疫功能的调节,促进患者康复,值得推广。
Objective To study the therapeutic effect and safety of modified Banxia Xiexin decoction in the treatment of chronic colitis.Methods A total of 98 randomized patients from January 2013 to December 2016 were randomly divided into two groups. The patients in the control group were treated with Western medicine. The patients in the observation group were treated with Banxia Xiexin decoction. The total effective rate,laboratory test indicators,the incidence of adverse reactions between the two groups was compared. Results After treatment of two months,the total effective rate in the observation group was 95. 92% which was higher than 79. 59% in the control group,and the incidence of adverse reactions in the observation group was 6. 12% which was lower than 22. 45% of the control group（ P〈 0. 05）. After 2 months＇ treatment,the levels of IL-1,IL-8 and TNF-α in the observation group were significantly lower than those in the control group,and the level of IL-10 in the observation group was higher than that of the control group（ P〈 0. 05）. Conclusion The application of traditional Chinese medicine Banxia Xiexin decoction is effective and safe in patients with chronic colitis,which can promote the regulation of immune function and promote the rehabilitation of patients.
出处
《光明中医》
2018年第1期1-3,共3页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
腹痛
泄泻
半夏泻心汤加减方
慢性结肠炎
安全性
细胞因子水平
Abdominal pain
Diarrhoea
Modified Banxia Xiexin decoction
Chronic colitis
Safety
Cytokine level
