摘要
目的探讨皮肌炎的临床特点。方法对160例皮肌炎临床表现及实验室检查结果进行分析。结果发病年龄(14~60)岁患者占74.38%;首发症状以单独皮疹为主(50%);皮肤损害以上眼睑为中心的特征性水肿性紫红斑多见(72.5%);肌肉受累以肌无力多见(95%),以四肢近端为主。内脏受累:心脏(52.5%)、肺部(20.6%)、消化道(21.9%),肾脏损害轻微。5%患者合并恶性肿瘤。乳酸脱氢酶(LDH)、天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、肌酸激酶(CK)、阳性率分别84.31%、73.87%、62.50%和44.35%。治疗以糖皮质类固醇激素为主。结论了解皮肌炎的发病特点,有利于临床中对皮肌炎的防控。
Objective To investigate the clinical characteristics of dermatomyositis（DM）. Methods The clinical manifestations and laboratory test results of 160 cases of DM hospitalized in Union Hospital were analyzed. Results Patients aged from 14 to 60 accounted for 74.38%, and women were more fre- quently affected than men. The first symptom was mainly single skin rash （50%）, and the most characteristic cutaneous features were heliotrope rash （72.5%）. Muscle involvement was mostly seen in muscle weakness （95%）, mainly in the proximal extremities. The visceral involvement was： the heart （52.5%）, the lung （20.6%）, the digestive tract （21.9%）, and the renal damage was slight. 5% patients were combined with malignant tumor. The positive rates of lactate dehydrogenase （LDH）, aspartate aminotransferase （AST）, alanine aminotransferase （ALT） and creatine kinase （CK） were 84.31%, 73.87%, 62.50% and 44.35%, respectively. The mainstay of therapy is corticosteroids. Conclusion To understand the characteristics of dermatomyositis, it is beneficial to the pre- vention and control of dermatomyositis in clinical.
出处
《皮肤病与性病》
2018年第1期1-3,共3页
Dermatology and Venereology
关键词
皮肌炎
临床
分析
Dermatomyositis~ Clinic
Analysis
