摘要
目的探讨预防性中央区淋巴结清扫对甲状腺乳头状癌复发率的影响。方法选取2015年3月~2017年9月我院收治的200例行甲状腺乳头状癌手术患者为研究对象,以是否进行预防性中央区淋巴结清扫为依据进行分组。观察组的100例患者进行预防性中央区淋巴结清扫,对照组的100例患者不进行预防性中央区淋巴结清扫,对两组患者的治疗情况及预后进行对比分析。结果观察组与对照组患者在是否伴有结节性甲状腺肿、是否伴有桥本氏甲状腺炎病理结果方面差异无统计学意义(P>0.05),观察组患者的肿瘤侵犯包膜率明显高于对照组(P<0.05);经随访,两组患者的并发症发生率比较,差异无统计学意义(P>0.05);观察组患者的术后复发率、远处转移率均明显低于对照组,组间差异有统计学意义(P<0.05)。结论在甲状腺乳头状癌术中实施预防性中央区淋巴结清扫治疗,可降低术后病灶转移率和疾病复发率,且不会明显增加手术并发症,远期效果显著,可在临床上进一步推广应用。
Objective To investigate the effect o on recurrence rate of prophylactic central lymph node dissection for papillary thyroid cancer. Methods A total of 200 cases with underwent operation of thyroid papillary carcinoma from March 2015 to September 2017 were selected as subjects and were grouped according to whether prophylactic central lymph node dissection.100 cases of the observation group were treated with prophylactic central lymph node dissection,and 100 cases of the control group were not treated with prophylactic central lymph node dissection.Treatment and prognosis between two groups were compared. Results Pathological results of combining with nodular goiter and Hashimoto’s thyroiditis of two group showed no significant difference（P 〉0.05）.Tumor invasion rate of the observation group was higher than that in the control group（P 〈0.05）.By following-up, complication rates between two groups showed no significant difference（P 〉0.05）.Postoperative recurrence rate and distant metastasis rate in the observation group were lower than those in the control group（P 〈0.05）. Conclusion Prophylactic central lymph node dissection in operation of thyroid papillary carcinoma can reduce the postoperative metastasis rate and the recurrence rate of the disease,and will not significantly increase the complications of the operation,and the long-term effect is significant,worthy of clinical promotion.
出处
《中国医药科学》
2017年第24期216-218,共3页
China Medicine And Pharmacy
关键词
中央区淋巴结清扫
甲状腺乳头状癌
复发率
远处转移
Central lymph node dissection
Papillary thyroid carcinoma
Recurrence rate
Distant metastasis
