摘要
目的评估2010与2015年江西省儿童恶性肿瘤的疾病负担情况及其变化趋势,为儿童恶性肿瘤防控提供依据。方法从中国分省份疾病负担研究数据中选取2010年和2015年江西省儿童恶性肿瘤的发病数、死亡数、过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY)等数据,使用2010年全国人口普查数据作为标准人口,计算标化的发病率、死亡率和DALY率,评价该省的恶性肿瘤发病、死亡和疾病负担的变化情况。结果 2010年、2015年江西省儿童恶性肿瘤的发病数、死亡数和DALY均呈现为男童>女童,5~14岁组>0~4岁组,但发病率、死亡率和DALY率均呈现为男童>女童,0~4岁组>5~14岁组。2015年儿童恶性肿瘤的标化发病率在0~4岁组下降6.66%,5~14岁组下降17.56%;标化死亡率在0~4岁组下降11.34%,5~14岁组下降21.78%;标化DALY率在0~4岁组下降11.27%,5~14岁组下降21.67%。2015年和2010年的儿童恶性肿瘤标化DALY率排在前三位的为白血病、脑癌和非霍奇金淋巴瘤。结论江西省需要重点防治的儿童恶性肿瘤是白血病、脑癌和非霍奇金淋巴瘤,5岁以下儿童和男童是重点防控对象,2015年疾病负担相对2010年有所下降。
Objective To study the burden of pediatric cancer in Jiangxi, China, in 2010 and 2015 and its changes from 2010 to 2015. Methods The data of pediatric cancer in Jiangxi in 2010 and 2015 were collected from the Global Burden of Disease Study 2015 in China, including number of cases, number of deaths, years of life lost（YLL）, years lived with disability（YLD）, and disability-adjusted life years（DALY）. The standardized incidence rate, mortality rate, and DALY rate were calculated with the national census data in 2010 as the standard population, in order to evaluate the changes in incidence, mortality, and disease burden of pediatric cancer in Jiangxi. Results In both 2010 and 2015, boys had higher numbers of cases, deaths, and DALY than girls, and the 5-14 years group had higher numbers than the 0-4 years group; boys had higher incidence rate, mortality rate, and DALY rate than girls, and the 0-4 years group had higher rates than the 5-14 years group. In 2015, the standardized incidence rate of pediatric cancer was reduced by 6.66% in the 0-4 years group and 17.56% in the 5-14 years group; the standardized mortality rate was reduced by 11.34% in the 0-4 years group and 21.78% in the 5-14 years group; the standardized DALY rate was reduced by 11.27% in the 0-4 years group and 21.67% in the 5-14 years group. Among the different types of pediatric cancer, leukemia had the highest standardized DALY rate in 2010 and 2015, followed by brain cancer and non-Hodgkin’s lymphoma. Conclusions There was a certain reduction in the burden of pediatric cancer in Jiangxi from 2010 to 2015. Leukemia, brain cancer, and non-Hodgkin’s lymphoma are the focus of prevention and treatment, and children aged less than 5 years and boys should be closely monitored.
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2018年第1期21-27,共7页
Chinese Journal of Contemporary Pediatrics
基金
江西省社会科学"十二五"规划项目(15GL18)
江西省高校人文社科规划项目(JC1551)
江西中医药大学校级自然科学基金研究项目(2014ZR014)
关键词
肿瘤
疾病负担
伤残调整寿命年
儿童
Cancer
Burden of disease
Disability-adjusted life year
Child
