摘要
侵袭性曲霉病(IA)是一种由曲霉菌引起的侵犯深部组织器官的预后极差的全身感染性疾病。早期准确诊断和及时的抗真菌治疗对改善曲霉菌感染患者的预后和降低病死率均具有重要意义。由于IA临床症状往往缺乏特异性,易被原发疾病掩盖,诊断主要依赖实验室检查,本文就目前应用于临床IA诊断的主要检测技术和未来有应用潜力的诊断技术做一介绍和评价,以期对IA早期诊断技术的临床应用和研究提供有益的帮助。
Invasive aspergillosis (IA) is a systemic infection disease caused by aspergillus, which attacks the deep tissue organs with poor prognosis. Early accurate diagnosis and timely antifungal treatment have great significance to improve the prognosis of patients with IA and reduce the mortality rate. Currently, the diagnosis of IA mainly depends on laboratory examination because the clinical manifestation of IA is almost lack of specificity, and easily masked by primary diseases. The main detection techniques of IA applied in clinic and diagnostic techniques with great potential application in the future were introduced and evaluated in this paper, so as to promote the IA diagnosis technology research and development.(Chin J Lab Med, 2018, 41: 9-12)
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2018年第1期9-12,共4页
Chinese Journal of Laboratory Medicine
基金
重庆市卫生计生委科研课题(2008-2-312)
重庆市渝中区基础和前沿研究课题(20160129)
关键词
侵袭性曲霉病
曲霉菌
实验室诊断
Invasive aspergillosis
Aspergillus
Molecular diagnostic techniques