摘要
目的采用Meta分析方法评价麻醉方式与术后谵妄(postoperative delirium,PD)、术后认知功能障碍(postoperative cognitive dysfunction,POCD)关系。方法使用中国知网、EMBASE和万方数据库检索麻醉方式、PD、POCD等关键词,评价纳入文献,使用STATA12.0进行Meta分析。结果检索到12项参考文献,全身麻醉(GA)和硬膜外麻醉(EPI)、联合麻醉(COM)以及脊柱麻醉(SPI)等局部麻醉(RA)对PD效应合并值为:OR=0.85,对POCD的效应合并值为:OR=1.38;GA会减少PD发生率,但是会增加POCD发生率。结论 Meta分析表明PD、POCD的发生与麻醉方式无相关性。
Objective To evaluate the relationship between postoperative delirium （PD） and postoperative cognitive dysfunction （postoperative cognitive dysfunction） by Meta analysis. Methods Using Chinese knowledge network, EMBASE and Wanfang database to retrieve anaesthesia, PD, POCD and other key words, evaluated the literature and use STATA12.0 for meta analysis. Results 12 references were retrieved. General anesthesia （GA） and epidural anesthesia （EPI）, combined anesthesia （COM） and spinal anesthesia （SPI） and other local anesthesia （RA） had a combined value of PD effect OR=0.85. The combined effect on POCD was OR = 1.38; GA reduced the incidence of PD, but increased the rate of POCD. Conclusion Meta analysis showed that there was no correlation between the occurrence of PD and POCD and the mode of anesthesia.
出处
《中国继续医学教育》
2017年第33期42-44,共3页
China Continuing Medical Education
