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TCL联用HPLC快速筛查止咳平喘制剂中9种非法添加成分的实验研究 被引量:4

Rapid Screenings of 9 Illegally Added Chemicals in Asthma Drug By TCL and HPLC
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摘要 目的:建立快速筛查止咳平喘中成药制剂中非法添加茶碱、醋酸泼尼松、醋酸地塞米松、倍他米松、二羟丙茶碱、盐酸克伦特罗、盐酸氨溴索、沙丁胺醇、色甘酸钠的分析方法。方法:先以TCL法二次展开进行初筛,后再用HPLC法进一步筛查确认。结果:TCL法和HPLC法的色谱条件均能有效分离上述9种成分。结论:此方法快速简便,可作为分析中成药制剂中非法添加茶碱、醋酸泼尼松、醋酸地塞米松、倍他米松、二羟丙茶碱、盐酸克伦特罗、盐酸氨溴索、沙丁胺醇、色甘酸钠的快速有效筛查方法。 Objective:To establish a rapid screening for cough and asthma added illegally in the proprietary Chinese medicine preparations,such as Theophylline,PrednisoneAcetate,Dexanietliasoiie Acetate,Betamethasone,Diprophylline,Clenbuterol hydrochloride,AmbroxolHydrochloride,Salbutamol,SodiumCromoglicate analysis method.Methods:start with TCL method secondary on screen at the beginning of HPLC to further screening of the reoccupy after confirmation.Results:The 9 kinds of ingredients can be effectively separated by TCL and HPLC method.Conclusion:this method is quick and easy,and can be used for analysis of proprietary Chinese medicine preparations illegally added Theophylline,PrednisoneAcetate,Dexanietliasoiie Acetate,Betamethasone,Diprophylline,Clenbuterol hydrochloride,AmbroxolHydrochloride,Salbutamol,SodiumCromoglicate fast effective screening method.
作者 汤珺
出处 《亚太传统医药》 2018年第1期31-34,共4页 Asia-Pacific Traditional Medicine
关键词 TCL法 HPLC法 止咳平喘制剂 非法添加化学物质 TCL HPLC Cough and Asthma Preparation Illegally Added Chemicals
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