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颅内未破裂动脉瘤介入术后微小脑梗死灶形成的危险因素分析 被引量:8

Risk factors of microembolism after endovascular coiling for unruptured intracranial aneurysms
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摘要 目的探讨颅内未破裂动脉瘤(unruptured intracranial aneurysms,UIA)介入术后微小脑梗死形成的危险因素。方法将238例经血管内介入弹簧圈栓塞的颅内UIA患者介入术后行核磁共振平扫检查,并根据检查表现分为无微小脑梗死灶组150例和有微小脑梗死灶组88例,对其临床资料进行回顾性分析;采用χ~2检验、t检验及logistic回归分析UIA介入术后微小脑梗死灶形成的危险因素。结果 UIA介入术后微小脑梗死灶的患者有37%,其中3%的微小脑梗死患者有相应的临床症状。Logistic回归分析显示2组患者年龄(P<0.001)、高血压病史(P=0.023)、糖尿病史(P=0.048)、脑卒中病史(P<0.001)及手术时间(P=0.007)是UIA介入术后微小脑梗死灶发生的危险因素。结论年龄、高血压病、糖尿病、脑卒中病史及手术时间是UIA介入术后微小脑梗死灶形成的危险因素。 Objective To investigate the risk factors of microembolism after endovascular coiling for unruptured intracranial aneurysms( UIA). Methods 238 patients suffered UIA for coil embolization inciuding microembolism negative group( n = 150) and microembolism positive group( n = 88),were examined by the MRI. Their clinical data were selected and analyzed respectively. Chisquare test,T test and Logistic regression analysis were used to analyze the risk factors of microembolism after endovascular coiling for UIA. Results The total rate of microembolism after endovascular coiling was 37%,in the microembolism positive group the total rate of neurological complication was 3%. Age( P〈0. 001),hypertension( P = 0. 023),hyperglycemia( P = 0. 048),previous stroke history( P〈0. 001) and procedure duration( P = 0. 007) were associated significantly with microembolism positive and they were the risk factors of microembolism after endovascular coiling for UIA which were proved by the logistic regression model. Conclusion Age,hypertension,hyperglycemia,previous stroke history and procedure duration were the risk factors of microembolism after endovascular coiling of UIA.
出处 《卒中与神经疾病》 2017年第6期508-511,共4页 Stroke and Nervous Diseases
关键词 颅内未破裂动脉瘤 介入治疗 微小脑梗死灶 危险因素 UIA Interventional therapy Microembolism Risk factors
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