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基于MRI的糖尿病合并急性脑梗死患者动脉粥样硬化分布情况与稳定性的临床研究 被引量:6

Clinical study on the distribution and stability of atherosclerosis in patients with diabetes and acute cerebral infarction based on magnetic resonance imaging
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摘要 目的分析MRI在糖尿病合并急性脑梗死动脉粥样硬化患者斑块分布情况检测应用中的有效性,并分析影响斑块稳定性的相关因素。材料与方法回顾性分析本院2018年1月至2020年1月收治的急性脑梗死且颈动脉粥样硬化斑块患者92例,其中单纯性急性脑梗死动脉粥样硬化患者34例,糖尿病合并急性脑梗死动脉粥样硬化患者58例。对比两组患者血管面积、斑块厚度、斑块长度、最狭窄处血管面积与狭窄率评估斑块分布情况,分析影响斑块稳定性的因素,包括高血压、高血脂、冠心病、饮酒史、性别和糖尿病等。结果 92例患者两侧出现斑块动脉数量为148支,单纯性急性脑梗死动脉粥样硬化组62支,合并糖尿病足86支。男性92支(46例),女性56支(28例),男性斑块率83.64%(46/55),女性斑块率75.68%(28/37),两组对比差异有统计学意义(P=0.013,t=6.872);其中单纯硬化组易损斑块比例70.97%(44/62),合并糖尿病组易损斑块比例83.72%(72/86),两组对比差异有统计学意义(P=0.001,t=7.671)。对照组(单纯组)梗死部位血管面积、斑块厚度、斑块长度、最狭窄处血管面积与狭窄率分别为(11.73±1.16) mm^2、(1.17±0.18) mm、(5.73±0.62) mm、(1.63±0.32) mm^2和(76.43±17.52)%,观察组(合并组)梗死部位血管面积、斑块厚度、斑块长度、最狭窄处血管面积与狭窄率分别为(12.15±1.18) mm^2、(1.34±0.17) mm、(6.83±0.69) mm、(1.14±0.35)mm2和(82.78±13.80)%。男性患者梗死部位血管面积、斑块厚度、斑块长度、最狭窄处血管面积与狭窄率分别为(11.86±1.25) mm^2、(1.12±0.17) mm、(5.72±0.83)mm、(1.43±0.25)mm2和(82.35±9.72)%,女性患者梗死部位血管面积、斑块厚度、斑块长度、最狭窄处血管面积与狭窄率分别为(11.53±1.28) mm2、(1.09±0.16)mm、(5.52±0.85)mm、(1.69±0.24)mm^2和(81.87±9.82)%。合并组患者血管狭窄程度高于单纯组,男性患者血管狭窄程度高于女性患者,差异有统计 Objective:To analyze the effectiveness of MRI in the detection of plaque distribution in patients with diabetes and acute cerebral infarction and atherosclerosis,and to analyze the relevant factors that affect plaque stability.Materials and Methods:A retrospective analysis of 92 patients with acute cerebral infarction and carotid atherosclerotic plaques admitted to our hospital during the period from January 2018 to January 2020,including 34 patients with simple acute cerebral infarction atherosclerosis,diabetes complicated with acute cerebral infarction atherosclerosis.There were 58 patients with type sclerosis.Compare the blood vessel area,plaque thickness,plaque length,the narrowest blood vessel area and stenosis rate between the two groups to evaluate the plaque distribution and analyze the factors affecting the stability of the plaque,including hypertension,hyperlipidemia,coronary heart disease,drinking history,gender and diabetes,etc.Results:The number of plaque arteries on both sides of the 92 patients was 148,62 in the simple acute cerebral infarction atherosclerosis group,and 86 with diabetic foot.Ninety-two males(46 cases),56 females(28 cases),male plaque rate 83.64%(46/55),female plaque rate 75.68%(28/37),the difference between the two groups was statistically significant(P=0.013,t=6.872);among them,the proportion of vulnerable plaques in the simple sclerosis group was70.97%(44/62),and the proportion of vulnerable plaques in the combined diabetes group was 83.72%(72/86).The difference between the two groups was statistically significant(P=0.001,t=7.671).In the control group(simple group),the area of the blood vessel at the infarct position,the thickness of the plaque,the length of the plaque,the area of the blood vessel at the most stenosis and the stenosis rate were(11.73±1.16)mm2,(1.17±0.18)mm,(5.73±0.62)mm,(1.63±0.32)mm2 and(76.43±17.52)%.In the observation group(combined group)the blood vessel area,plaque thickness,plaque length,the most stenosis blood vessel area and stenosis rate were(12.15�
作者 陈露萍 孙家元 杨志勇 张芾 朱蓓 蒋艺兰 CHEN Luping;SUN Jiayuan;YANG Zhiyong;ZHANG Fu;ZHU Bei;JIANG Yilan(People's Hospital of Rugao City,Rugao 226500,Jiangsu,China)
机构地区 如皋市人民医院
出处 《磁共振成像》 CAS 2020年第12期1159-1162,共4页 Chinese Journal of Magnetic Resonance Imaging
关键词 磁共振成像 糖尿病 急性脑梗死 动脉粥样硬化 斑块 magnetic resonance imaging diabetes acute cerebral infarction atherosclerosis plaque
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