摘要
目的探讨孟鲁司特钠在过敏性鼻炎合并过敏性结膜炎的治疗效果。方法采用随机数字表法将124例过敏性鼻炎合并过敏性结膜炎患者分为对照组与实验组各62例,对照组给予布地奈德喷鼻剂喷鼻+氯替泼诺滴眼液滴双眼,4次/d,实验组在对照组的基础上,加孟鲁司特,10 mg,口服,1次/d,疗程1个月,比较两组患者的临床疗效。结果实验组有效率为96.8%,显著高于对照组77.4%,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论孟鲁司特钠对过敏性鼻炎及过敏性结膜炎的治疗均有促进作用,副作用未增加。
Objective To investigate the therapeutic effect of montelukast sodium on allergic rhinitis with allergic conjunctivitis. Methods A total of 124 patients with allergic rhinitis and allergic conjunctivitis were randomly divided into control group and experimental group with 62 cases in each group. The control group was given budesonide nasal spray＋ loteprednol eyedrops Eyes,4 times a day,the experimental group in the control group based on the plus montelukast,10 mg,orally,1 times a day,course of treatment for one month,the clinical efficacy of the two groups were compared. Results The effective rate of the experimental group was 96. 8%,which was significantly higher than that of the control group（ 77. 4%）,the difference was statistically significant（ P〈 0. 05）. There was no significant difference between the two groups in the incidence of adverse reactions（ P〉 0. 05）. Conclusion Montelukast sodium can promote the treatment of allergic rhinitis and allergic conjunctivitis,with no increase of side effects.
出处
《延安大学学报（医学科学版）》
2017年第4期49-51,共3页
Journal of Yan'an University:Medical Science Edition
