摘要
目的探讨寻常型银屑病患者血液中相关指标变化特点及其在临床中的意义。方法收集38例通过临床及组织病理诊断明确的寻常型银屑病患者,并对其进行疾病严重程度评分(PASI),及40例健康体检者血中性粒细胞/淋巴细胞比值(NLR)、C-反应蛋白(CRP)、总胆固醇、甘油三酯、血尿酸值,比较两组中上述指标,并采用Pearson相关性分析PASI评分与CRP、NLR、血脂、血尿酸间的关系。结果寻常型银屑病患者NLR、总胆固醇、甘油三酯、血尿酸均明显高于对照组(P<0.05)。PASI评分与NLR间呈正相关(P<0.05),CRP与NLR及PASI评分与CRP间无相关性(P>0.05)。PASI评分≥7分的患者,其血尿酸水平比<7分者更高。结论 NLR能反映寻常型银屑病患者病情及系统炎症状态,病情越重者血尿酸水平越高。
Objective To investigate the characteristics and the clinical significance of relevant parame-ters of blood in psoriasis vulgaris（PV）. Methods A retrospective analysis among 38 PV patients and 40 normal controls was done. The comparing parameters contained NLR,CRP,total cholesterol,triglyceride,serum uric acid.Pearson correlation analysis was used to detect the correlations.Results NLR,total cholesterol,triglyceride, serum uric acid in psoriasis vulgaris patients were significantly higher than in the normal controls（P 〈 0.05）. There was a statistically significant correlation between NLR and PASI in the PV patients,but no correlation of CRP with NLR and PASI（P 〉 0.05）. In the patients with PASI ≥ 7,the serum uric acid level was significantly higher than in those with PASI 〈 7. Conclusions NLR is indicateive of the severity and state of inflammation. The severer PV,the higher the level of serum uric acid.
出处
《实用医学杂志》
CAS
北大核心
2017年第24期4061-4064,共4页
The Journal of Practical Medicine
基金
西南医科大学附属医院院内基金(编号:2015-QS-035)
