摘要
目的:探究血清肿瘤标志物CEA、CA19-9、CA242、CA724联合检测对胃癌的诊断效果。方法:随机抽取2013年2月~2016年2月某科室的30例胃癌患者作为实验组,同期选取30例慢性萎缩性胃炎患者作为对照组,采用全自动生化仪对所有研究样本的CA19-9、CA242、CA724及CEA指标进行检测,评估两组患者的CA19-9、CA242、CA724和CEA水平,各项血清肿瘤标志物的灵敏度和特异度。结果:实验组患者的CA19-9、CA242、CA724及CEA指标显著高于对照组(P<0.05)。结论:胃癌患者的CA19-9、CA242、CA724及CEA水平会有明显的升高现象,临床上早期对胃癌患者CA19-9、CA242、CA724及CEA水平进行有效的监测,可有效反映患者疾病的发展进程,判断患者的疾病发展程度,临床意义显著。
Objective：To explore the effect of combined detection of serum tumor markers CEA, CA19-9, CA242, and CA724 in the diagnosis of gastric cancer. Methods：30 cases of patients with gastric cancer treated in a hospital from February 2013 to February 2016 were randomly selected as the experimental group,at the same time,30 cases of patients with chronic atrophic gastritis were selected as the corresponding group.The CA19-9, CA242, CA724, and CEA indexes of all the research samples were detected by an automatic bio chemical analyzer,then the CA19-9, CA242, CA724, and CEA levels, the sensitivity, and specificity in the two groups were evaluated.Results： The CA19-9, CA242, CA724, and CEA indexes of the patients in the experimental group were significantly higher than those in the corresponding group （P〈0.05）.Conclusion： The levels of CA19-9, CA242, CA724 and CEA in patients with gastric cancer were significantly elevated.Clinically,early monitoring of CA19-9, CA242, CA724 and CEA levels in gastric cancer patients can effectively reflect the progression of disease and determine the degree of disease development, with significant clinical significance.
出处
《数理医药学杂志》
2018年第1期47-48,共2页
Journal of Mathematical Medicine
