摘要
目的检测本院908例呼吸道感染患者九项呼吸道病原体的Ig M抗体,从而了解九种病原体的流行特征。方法采用间接免疫荧光法对908例呼吸道感染患者血液中九项病原体的Ig M抗体进行检测分析。结果本研究呼吸道感染患者血清Ig M抗体检测总阳性率为36.1%(328/908),合并感染率为13.4%(122/908),在阳性病例中占37.2%(122/328)。INFB+PIVS合并感染最为常见。春夏季以INFB流行为主,秋冬季以PIVS流行为主。不同季节病原体检测阳性率差异有统计学意义(P<0.05)。秋冬季的阳性率高于春夏季。≤25岁年龄组和≥65岁年龄组人群最易感染INFB,26~64岁年龄组人群最易感染LP1。3个年龄组的阳性率差异有统计学意义(P<0.05)。不同性别病原体检测阳性率之间差异没有统计学意义(P>0.05)。结论重点季节预防相应病原体的流行和传播,持续监测病原体的Ig M抗体有利于更好防控。
Objective To explore the epidemiology of IgM antibodies of nine species of respiratory tract pathogens in 908 Patients. Methods Nine of pathogen IgM antibodies in serum of 908 Patients diagnosed as respiratory tract infections were tested by indirect immunofluorescence assay. Results Of total 908 serum specimens detected, there were 328 positive with the positive rate of 36.1%. The rate of combined infection was 13.4% （122/908） in 908 Patients,37.2% （ 122/328 ） in positive cases. The combination of INFB and PIVS was most common. During spring and summer, it was dominated by the Influenza B （INFB）, which was dominated by Parainfluenzal, 2 and 3 （PIVs）. The positive rates of different pathogens were statistically significant in different seasons （ P 〈 0.05 ）. The positive rate in autumn and winter was higher than which in spring and summer. The patients aged less than 25 years and more than 65 years were the most susceptible to INFB ,while the patients aged from 26 to 64 years were the most susceptible to Legionella pneumophila serogroup 1 （ LP1 ）. The positive rate of the three groups was significantly different（ P 〈 0.05 ）. The positive rates of different pathogens were significantly different in different sex （ P 〉 0.05 ）. Conclusion To achieve the better protection and to prevent the prevalence and spread of the corresponding pathogens in their peak seasons, continuous monitoring of pathogen IgM antibodies is important.
出处
《标记免疫分析与临床》
CAS
2017年第11期1212-1215,共4页
Labeled Immunoassays and Clinical Medicine
