摘要
染色体核型分析已被广泛应用于临床及产前细胞遗传学诊断。为了提高染色体核型制备的质量，国内外学者在不断地摸索改进染色体培养、制备和分析的方法，一些大的研究中心开始制定相应的质量控制标准。为使更多的细胞遗传工作者了解这些进展，本文对近十年间相关领域的进展做一综述。
Chromosome analysis has been widely used in clinics including prenatal diagnosis. To obtain high-quality metaphase chromosomes, researchers have attempted to modify the methods for chromosome culture, preparation and analysis. Some large research centers also tried to establish standards for quality control. In this paper, modification of methods for the preparation of chromosomes in the last decade is reviewed.
出处
《中华医学遗传学杂志》
CAS
CSCD
北大核心
2017年第6期915-918,共4页
Chinese Journal of Medical Genetics
关键词
染色体
质量控制
改良
细胞遗传学
分裂相
Chromosome~ Quality control
Modification
Cytogenetics
Metaphase
