摘要
目的了解新生儿室多重耐药菌构成及变化趋势,为多重耐药菌的防治提供依据。方法采用回顾性分析,对2011—2016年某院新生儿室送检的各类标本分离的多重耐药菌进行统计分析。结果共分离出多重耐药菌株286株,主要为产超广谱β-内酰胺酶(ESBLs)阴性菌株,产ESBLs大肠埃希菌最多(118株),其次是产ESBLs肺炎克雷伯菌(91株)和耐甲氧西林金黄色葡萄球菌(70株)。产ESBLs大肠埃希菌数量逐年增多。多重耐药菌多来自痰液(83.22%)。结论新生儿室多重耐药菌检出数量逐年增加,为控制多重耐药菌的产生及院内感染,需加强抗菌药物使用与检测,加强手卫生。
Objective To understand the composition and change trend of multidrug-resistant bacteria in neonatal department,and to provide a basis for the prevention and treatment of multidrug-resistant bacteria.Methods A retrospective investigation was performed to analyze the multidrug-resistant bacteria isolated from samples in neonatal department of a hospital from 2011 to2016.Results A total of 286 strains of multidrug-resistance bacteria were isolated,and most of them are negative bacteria producing extended-spectrumβ-lactamases(ESBLs),mainly including ESBLs-producing E.coli(118 strains),ESBLs-producing K.pneumoniae(91 strains)and methicillin-resistant Staphylococcus aureus(70 strains).The number of ESBLs-producing E.coli strains increased year by year.Multidrug-resistant bacteria were mainly found in sputum specimens(83.22%).Conclusion The number of multidrug-resistant bacteria increases year by year in neonatal department.The rational antimicrobial agent use and hand hygiene should be strengthened to control the nosocomial infections caused by multidrug-resistant bacteria.
出处
《实用临床医学（江西）》
CAS
2017年第9期52-55,共4页
Practical Clinical Medicine
关键词
多重耐药菌
新生儿室
防控措施
multidrug-resistant bacteria
neonatal department
prevention and control measures
