摘要
目的分析贵州省含麻疹成分疫苗(MCV)免疫失败麻疹病例的流行病学特征。方法对2010-2015年麻疹监测报告信息管理系统中麻疹病例个案资料进行收集整理,采用描述性流行病学法分析。结果 2010-2015年贵州省报告MCV免疫失败麻疹病例88例,占麻疹病例总数的13.15%。免疫失败病例分布在全省8个市(州)35个县,各市(州)免疫失败病例在麻疹总病例中构成比在0.00%(铜仁)-20.75%(黔南)之间(χ~2=33.96,P=0.000);各年龄组在7.23%(>14岁)-34.28%(2-6岁)之间(χ~2=44.89,P=0.000)。免疫失败病例与麻疹总病例的月分布一致(r=0.74,P=0.006)。接种过1剂次、≥2剂次MCV的免疫失败病例分别占59.09%、40.91%。结论贵州省MCV免疫失败病例在麻疹病例中占一定比例,需进一步提高MCV预防接种质量。
Objective To analyze the epidemiological characteristics of measles cases with failure of mea- sles containing vaccine （MCV） in Guizhou. Methods Data of measles cases during 2010-2015 were collected by the Measles Surveillance Information Reporting and Management System, and were analyzed by descriptive epidemiological methods. Results Eighty-eight measles cases with measles vaccine failure were reported in Guizhou during 2010-2015, accounting for 13.15% of all reported measles cases. Vac- cine failure cases came from 35 counties of 8 prefectures. The proportion of vaccine failure cases ranged from 0.00% in Tongren to 20. 75% in Qiannan （x^2 = 33.96, P = 0. 000 ） , and from 7.23% among 〉 14 year olds to 34. 28% among 2-6 year olds （x^2 =44. 89, P =0. 000）. The monthly distribution of vaccine failure cases was similar to that of all measles cases （ r = 0. 74, P = 0. 006 ）. Among vaccine failure cases, 59.09% received 1 dose of MCV, and 40.91% received 〉12 doses. Conclusions Cases with measles vaccine failure were found among measles cases. The quality of MCV vaccination should be improved.
作者
戴丽芳
张大勇
杜雯
唐小敏
Dai Li- fang;Zhang Dayong;Du Wen;et al.(Guizhou Provincial Center for Disease Control and Prevention, Guiyang 550004, Guizhou, Chin)
出处
《中国疫苗和免疫》
北大核心
2017年第5期530-533,共4页
Chinese Journal of Vaccines and Immunization
关键词
麻疹
含麻疹成分疫苗
免疫失败
流行病学特征
Measles
Measles containing vaccine
Vaccine failure
Epidemiological characteristics
