摘要
卵巢早衰是一种妇科的常见疾病,也是不孕不育的主要因素之一。其发病原因复杂,发病率逐年升高,给患者、家庭和社会造成了许多不良的影响。关于对卵巢早衰的治疗目前主要停留在激素维持治疗的阶段,尚无根治该病的方法。拥有可再生功能的干细胞目前越来越多地被应用于卵巢早衰临床前的实验研究,且取得了不错的进展。间充质干细胞作为干细胞家族的重要分支,有望成为卵巢早衰治疗的重要材料。本文基于总结近年来不同来源的间充质干细胞在治疗卵巢早衰方面的临床前研究成果,提出其在该领域的发展前景,希望对卵巢早衰的研究和治疗提供参考。
Premature ovarian failure（POF）is a common disease of gynecology and one of the main causes for sterility. It happens for complicated causes and increases year after year so that patients, families and society get many bad infuences. At present, the therapy to POF is mainly maintaining the step of hormone therapy, but there is not a method of radical treatment at all. Stem cells with renewable functions are more and more used for preclinical researches about POF, which have got well advances. Mesenchymal stem cell as an important branch of stem cell family would become important materials for POF therapy. Here is to make a summary of research findings of mesenchymal stem cells from different sources in therapying POF, and Its development prospects in the feld are put forward, in order to provide references for studies and therapies to POF.
出处
《实用妇科内分泌电子杂志》
2016年第19期16-17,共2页
Electronic Journal of Practical Gynecological Endocrinology
关键词
间充质干细胞
卵巢早衰
临床前研究
Mesenchymal stem cell
Premature ovarian failure
Preclinical research
