摘要
目的:观察加味麻黄附子细辛汤联合富马酸福莫特罗干粉吸入治疗老年支气管哮喘的临床疗效。方法:选取120例老年支气管哮喘患者为研究对象,随机分为对照组与观察组,每组60例。对照组采用小剂量富马酸福莫特罗粉吸入剂吸入治疗,观察组采取加味麻黄附子细辛汤联合小剂量富马酸福莫特罗粉吸入剂吸入治疗。观察2组临床症状的缓解时间及治疗前后肺功能指标[1秒用力呼气容积(FEV1)、最大呼气流量(PEF)]的变化,评估治疗效果。结果:观察组咳嗽、喘息、胸闷缓解时间均短于对照组(P<0.05)。治疗后,2组FEV_1及PEF均较治疗前升高(P<0.05),观察组的2项肺功能指标水平均比对照组升高更显著(P<0.05)。观察组治疗总有效率98.33%,高于对照组的80.00%,差异有统计学意义(P<0.05)。结论:加味麻黄附子细辛汤联合富马酸福莫特罗粉吸入剂吸入治疗老年支气管哮喘,临床疗效显著,可有效改善患者的各项临床症状及肺功能。
Objective:To observe the clinical effect of modified Mahuang Fuzi Xixin tang combined with formoterol single inhaler for senile bronchial asthma. Methods: Selected 120 cases of senile bronchial asthma patients as study objects, and divided them into the observation group and the control group randomly, 60 cases in each group. The control group was treated with formoterol fumarate powder for inhalation of low dose, while the observation group was treated with modified Mahuang Fuzi Xixin tang combined with formoterol fumarate powder for inhalation of low dose. Observed time of clinical symptoms relieved and change in level of pulmonary function indexes which includes forced expiratory volume in one second (FEVl) and peak expiratory flow(PEF) of both groups before and after treatment, and evaluated curative effect. Results. Remission time of cough, wheezing, dyspnea of the observation group were all shorter than those of the control group(P〈 0.05). After treatment, levels of FEVl and PEF in both groups were higher than those before treatment(P〈0.05). Increase of levels of the two pulmonary function indexes in the observation group was more significant than that of the control group(P〈 0.05). The total effective rate was 98.33% in the observation group, and was 80.00% in the control group, the difference being significant (P 〈0.05). Conclusion: Modified Mahuang Fuzi Xixin tang combined with formoterol fumarate powder for inhalation has significant curative effect in treating senile bronchial asthma. It can effectively improve clinical symptoms and pulmonary function of patients.
出处
《新中医》
CAS
2017年第11期38-40,共3页
New Chinese Medicine
关键词
支气管哮喘
老年人
中西医结合疗法
加味麻黄附子细辛汤
富马酸福莫特罗粉吸入剂
肺功能
Bronchial asthma
Elderly
Integrated Chinese and western medicine therapy
Modified Mahuang Fuzi Xixintang
Formoterol fumarate powder for inhalation
Pulmonary function