摘要
目的分析扬州地区儿童呼吸道感染病毒病原体的感染情况。方法应用直接免疫荧光法检测2011年1月—2016年12月扬州地区17 691例呼吸道感染儿童鼻咽分泌物呼吸道腺病毒(ADV)、合胞病毒(RSV)、副流感病毒Ⅰ、Ⅱ、Ⅲ(PIVⅠ、Ⅱ、Ⅲ)、流感病毒A/B(IFA/B)病毒抗原并分析其流行病学特征。结果在17 691例标本中,共检出病毒阳性标本1 991例,检出率11.25%(1 991/17 691);在1 991例阳性标本中,RSV占60.12%(1 197/1 991),其他依次为PIVⅢ14.27%(284/1 991)、ADV 8.04%(160/1 991)、PIVⅠ5.42%(108/1 991)、IFA 5.27%(105/1 991)、IFB 4.07%(81/1 991)、PIVⅡ2.81%(56/1 991)。RSV检出率存在性别差异。1月~<1岁组呼吸道病毒检出病例占总检出率的59.81%(1 191/1 991);单项病毒检出率在4组人群中均居首位。冬季是检出病毒阳性占比最高的季节,为51.88%(1 033/1 991);夏季检出率最低,为10.35%(206/1 991)。结论扬州地区呼吸道病毒感染受年龄、季节和性别的影响,RSV感染最多见,以1月~<1岁婴幼儿为主,冬季好发,并且男性较女性更易感。
ObjectiveTo investigate multiple viral antigens in pediatric patients with respiratory infection in Yangzhou. MethodsA total of 17 691 children with respiratory infection admitted in our hospital between January 2011 and December 2011 were tested with direct immunof luorescence method. A total of 7 kinds of virus antigens were detected, including adenovirus （ADV）, respiratory syncytial virus （RSV）, parainfluenza virusⅠ, Ⅱ, Ⅲ（PIV Ⅰ, Ⅱ, Ⅲ）, influenza virus A/B（IFA/B）. Its epidemiological characteristics was analyzed. ResultsThere were altogether 1 991 positive cases, the detection rate was 11.25%（1 991/17 691）, in which the proportion of RSV was 60.12% （1 197/1991）, followed by PIV Ⅲ 14.27% （284/1 991）, ADV 8.04%（160/1 991）, PIVⅠ5.42% （108/1 991）, IFA5.27% （105/1 991）, IFB 4.07% （81/1 991）, PIVⅡ 2.81% （56/1 991）. There was significant difference between male and female in the detection rate of respiratory virus. Respiratory virus detected rate in 1 month to〈1 year old was 59.81% （1 191/1 991）, single virus detection rate was the highest. The detection rate of virus for positive was the highest in winter, accounting for 51.88%（1 033/1 991）, and the lowest in summer for 10.35%（206/1 991）. ConclusionRespiratory virus infection in Yangzhou is influenced by age, season and gender, with infants and young children aged 1 month to 1 year in high risk infection, and RSV infection occurs mostly, and the male are most likely to be infected in winter.
作者
程文国
陈剑
刘艳
朱新林
诸俊
CHENG Wenguo;CHEN Jian;LIU Yan;ZHU Xinlin;ZHU Jun(Laboratory Department , Affiliated Hospital of Yangzhou University,Yangzhou Maternal and Child Health Care Hospital,Yangzhou, Jiangsu,22500)
出处
《实用临床医药杂志》
CAS
2017年第19期87-90,共4页
Journal of Clinical Medicine in Practice
关键词
呼吸道感染
儿童
病毒
直接免疫荧光法
respiratory tract infections
children
viruses
direct immunofluorescence assay
