摘要
目的观察调理脾胃针法治疗早期2型糖尿病足(DF)的临床疗效。方法将100例早期2型DF患者随机分为治疗组和对照组,每组50例。两组均接受常规糖尿病治疗,治疗组在此基础上采用调理脾胃针法治疗,对照组采用口服胰激肽原酶肠溶片治疗。治疗6星期后,观察两组治疗前后空腹血糖(FBG)、餐后2 h血糖(P2BG)、血清总胆固醇(TC)、甘油三酯(TG)、6-酮-前列腺素(6-keto-PGF1?)及血栓素B2(TXB2)含量的变化情况,并比较两组临床疗效。结果治疗组总有效率为91.8%,对照组为75.5%,两组比较差异具有统计学意义(P<0.05)。两组治疗后各项指标(FBG、P2BG、TC、TG、6-keto-PGF1?、TXB2)与同组治疗前比较,差异均具有统计学意义(P<0.01,P<0.05)。治疗组治疗后各项指标与对照组比较,差异均具有统计学意义(P<0.01,P<0.05)。结论调理脾胃针法是一种治疗早期2型DF的有效方法,可改善糖代谢异常造成的进行性损害。
Objective To observe the clinical efficacy of needling method of regulating spleen-stomach in treating early-stage type 2 diabetic foot （DF）. Method A hundred patients with early-stage type 2 DF were randomized into a treatment group and a control group, 50 cases each. The two groups both received conventional treatment for diabetes. In addition, the treatment group was intervened by needling method of regulating spleen-stomach; the control group was given oral administration of Pancreatic kininogenase enteric-coated tablets. After 6-week treatment, the changes in fasting blood glucose （FBG）, 2-hour postprandial blood glucose （P2hBG）, serum total cholesterol （TC）, triglyceride （TG）, 6-keto-PGF1α and thromboxane B2 （TXB2） contents were observed. The clinical efficacies of the two groups were also compared. Result The total effective rate was 91.8% in the treatment group versus 75.5% in the control group, and the between-group difference was statistically significant （P〈0.05）. The levels of FBG, P2hBG, TC, TG, 6-keto-PGF1α and TXB2 were significantly changed after the intervention in the two groups （P〈0.01,P〈0.05）. The treatment group was significantly different from the control group in comparing each parameter after the intervention （P〈0.01,P〈0.05）. Conclusion Needling method of regulating spleen-stomach is an effective method in treating early-stage type 2 DF, and can improve the progressive injury induced by abnormal glucose metabolism.
作者
李思
杨元庆
薛莉
李洁
周星娅
张智龙
LI Si;YANG Yuan- qing;XUE Li;LI Jie;ZHOU Xing-ya;ZHANG Zhi-long(Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine,Tianjin 300120,China)
出处
《上海针灸杂志》
2017年第11期1290-1294,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家自然科学基金项目(81373784)
天津市中医药管理局中医
中西医结合科研专项课题(15011)
关键词
针刺疗法
糖尿病
2型
糖尿病足
糖尿病并发症
空腹血糖
餐后2
h血糖
胆固醇
6-酮-前列腺素
甘油三酯
血栓素B2
Acupuncture therapy
Diabetes, Type 2
Diabetic foot
Diabetic complications
Fasting blood glucose
2-hour postprandial blood glucose
Cholesterol
Triglyceride
6-keto-PGF1α
Thromboxane B2
