摘要
目的:分析早产儿血清维生素A水平与新生儿呼吸窘迫综合征(NRDS)的发生及病情严重程度的相关性。方法:选择2013年至2015年我院儿科收治的82例早产儿作为研究对象,根据临床特征及胸部X线片结果,将患儿分为NRDS组和非NRDS组各41例,测定两组患儿的血清维生素A水平,分析NRDS患儿血清维生素A水平与病情严重程度的相关性。结果:胎龄34~36周早产儿,NRDS组血清维生素A水平明显低于非NRDS组(P<0.05),NRDS组中病情较轻的新生儿血清维生素A水平高于病情严重的新生儿(P>0.05),血清维生素A不足0.7μmol/L的新生儿NRDS发生率较高。NRDS患儿维生素A<0.35μmol/L时的发病率为29.27%,维生素A≥0.35μmol/L的发病率为20.76%(P<0.05)。结论:血清维生素A水平相对较低的新生儿更容易发生NRDS。
Objective： To study the correlation between serum vitamin A level and the severity of neonatal respiratory distress syndrome（ NRDS）. Methods： Eighty-two cases of premature infants from 2013 to 2015 in our hospital of pediatrics were selected as the research object,according to the clinical characteristics and chest X ratios examination results,children were divided into NRDS group（ 41 cases） and non NRDS group（ 41 cases）. Serum vitamin A levels of two groups were measured and compared in two groups,to study the correlation between serum vitamin A level and the severity of neonatal respiratory distress syndrome（ NRDS）. Results： The gestational age of 34 ~ 36 weeks premature,the level of serum vitamin A in NRDS group was significantly lower than non NRDS group（ P〈0. 05）,the level of serum vitamin A of mild neonatal newborn in NRDS group was higher than that of severe neonatal newborn（ P〉0. 05）. The incidence of NRDS in children with vitamin A〈0. 7 mol/L was higher. The incidence of NRDS in children with vitamin A〈0. 35 mol/L was 29. 27%,the incidence of vitamin A more than 0. 35 mol/L was 20. 76%（ P 〈 0. 05）. Conclusion： Neonates with relatively low serum vitamin A levels are more likely to develop respiratory distress syndrome.
作者
江雪
Jiang Xue(Meishan City Maternal and Child Health Care Hospital, Sichuan Meishan 620010, China)
出处
《儿科药学杂志》
CAS
2017年第11期22-24,共3页
Journal of Pediatric Pharmacy
关键词
早产儿
维生素A
新生儿呼吸窘迫综合征
相关性
premature infant
vitamin A
neonatal respiratory distress syndrome
correlation
