摘要
目的:对中药连翘的化学成分进行研究。方法:利用大孔吸附树脂、硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱和制备液相等色谱手段进行分离纯化,根据化合物的理化性质和波谱学等方法鉴定其结构。结果:从木犀科连翘属植物连翘的95%乙醇提取物中分离得到6个化合物,分别鉴定为对羟基苯甲酸(1),对乙醇基苯甲醛(2),对羟基苯乙酸(3),对香豆酸(4),对羟基苯基乙酸乙酯(5),1-(4-羟基苯基)-2,3-二羟基丙酮(6)。结论:化合物2、5、6为首次从连翘属(Forsythia)中分离得到。
Objective： To isolate and identify the compounds from the Forsythia suspensa （Thuni）.） Vahl. Methods： The com-pounds were separated and purified by column chromatography and their structures were established by spectroscopic methods. Re-sults： Six compounds were obtained from the 95% ethanol-water extracts of the Forsythia suspensa （Thunb.） Vahl. The structures were determined as 4-Hydroxybenzoic acid （1）, p-hydroxyethyl benzaldehyde （2）, 4-Hydroxyphenylacetic acid （3）, p-Hydroxycinnamic ac-id （4）, Ethyl 4-hydroxyphenylacetate （5）, l-（4-Hydroxyphenyl）-2,3-dihydroxy-propanone （6）. Conclusion： Compounds 2,5 and 6 were isolated from the genus Forsythia for the first time.
出处
《黑龙江医药》
CAS
2016年第4期601-602,共2页
Heilongjiang Medicine journal
关键词
连翘
化学成分
成分分离
结构鉴定
Forsythia suspensa （Thunb.） vahl
structural identification
constituent isolation
chromatography
