期刊文献+

孟鲁司特联合布地奈德对咳嗽变异性哮喘患儿血清炎性因子及肺功能的影响 被引量:7

The effect of montelukast combined with budesonide on serum inflammatory factors and pulmonary function of children with cough variant asthma
下载PDF
导出
摘要 目的观察孟鲁司特联合布地奈德对咳嗽变异性哮喘患儿血清炎性因子与肺功能的影响。方法选取本院2015年3月至2017年1月收治的咳嗽变异性哮喘患儿90例,根据随机数表法分为观察组及对照组,各45例。两组患儿均施以常规治疗联合孟鲁司特,观察组加用布地奈德,比较两组血清炎性因子及肺功能改善情况及不良反应。结果治疗后,观察组血清炎性因子水平低于对照组,肺功能改善优于对照组,差异有统计学意义(P〈0.05);两组患儿在治疗中不良反应发生情况比较差异无统计学意义(P〉0.05)。结论孟鲁司特联合布地奈德治疗咳嗽变异性哮喘,患儿血清炎性因子水平明显降低,肺功能得到明显改善,联合用药疗效显著,且联合用药不会增加患儿不良反应,安全性高。
作者 刘蕾 Liu Lei(Department of Pediatrics, The First Affiliated Hospital of Nanyang Medical College, Nanyang 473000, Chin)
出处 《国际医药卫生导报》 2017年第22期3580-3582,共3页 International Medicine and Health Guidance News
  • 相关文献

参考文献8

二级参考文献74

  • 1吴桦,王水利,韩雪芳.白三烯受体拮抗剂在哮喘治疗中的地位和前景[J].医学综述,2006,12(19):1198-1199. 被引量:7
  • 2Nakajima T,Nishiuma Y,Nishiuma T,et al.Cough sensitivity in pure cough variant asthma elicited using continuous capsaicin inhalation[J].Allergol Int,2006,55(2):149-155. 被引量:1
  • 3Takemura M, Niimi A, Matsumoto H, et al. Clinical, physio- logical and anti-inflammatory effect of montelukast in patients with cough variant asthma [J]. Respiration, 2012, 83 (4) : 308-315. 被引量:1
  • 4Tagaya E,Kondo M,Kirishi S,et al.Effects of regular treatment with combination of salmeterol/fluticasone propionate and salmeterol alone in cough variant asthma[J].J Asthma,2014,52(5):1-21. 被引量:1
  • 5Takemura M,Niimi A,Matsumoto H,et al.Clinical physiological and anti-inflammatory effect of montelukast in patients with cough variant asthma[J].Respiration,2012,83(4):308-315. 被引量:1
  • 6Bao W,Chen Q,Lin Y,et al.Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma[J].Respirology,2013,18(Suppl 3):53-61. 被引量:1
  • 7Niimi A.Cough and Asthma[J].Curr Respir Med Rev,2011,7(1):47-54. 被引量:1
  • 8Hon KL,Leung TF,Leung AK.Clinical effectiveness and safety of montelukast in asthma.What are the conclusions from clinical trials and meta-analyses?[J].Drug Des Devel Ther,2014,8(4):839-850. 被引量:1
  • 9Irwin RS, Baumann MH, Bolser DC, et al. Diagnosis and managementof cough executive summary: ACCP evidence-based clinical practiceguidelines[j]. Chest, 2006,129( 1 Suppl):lS-23S. 被引量:1
  • 10Takemura M, Niimi A, Matsumoto H, et al. Clinical, physiological andanti-inflammatory effect of montelukast in patients with cough variantasthma[j]. Respiration, 2012,83(4): 308-315. 被引量:1

共引文献422

同被引文献61

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部