摘要
结直肠癌患者中肺是继肝脏之后最常见的远处转移器官之一,但由于肺转移发病率较低且生物学侵袭性相对温和,因而与结直肠癌肝转移相比,结直肠癌肺转移无论是关注程度、综合治疗理念还是相关的临床和基础研究都相对匮乏。本文现介绍1例直肠癌伴同时性多发性肺转移患者在浙江大学医学院附属第二医院大肠癌诊治中心的多学科综合治疗(multidisciplinary team,MDT)经过,以探讨该类患者的临床病理特征、预后影响因素、合理的综合治疗决策以及现有的诊治争议与共识,以期促进临床诊疗的规范化和个体化,使患者更多获益。
Lungs are the second most common distant metastatic organs of colorectal cancer, following the liver. However, clinical researches on lung metastasis are insufficient comparing with that on liver metastasis due to its low occurrence and relatively mild biological behavior. This paper aims to investigate the clinicopathological characteristics and prognostic factors of rectal cancer patients with multiple synchronous lung metastases. The patient was from the Second Affiliated Hospital of Zhejiang University, School of Medicine underwent multi-disciplinary diagnosis and treatment. Moreover, this article aims to discuss the related existing consensus and controversies on this issue.
作者
袁瑛
徐栋
杨琦
贝迪恺
刘月
张苏展
丁克峰
Ying YUAN Dong XU O.i YANG Dikai BEI Yue LIU Suzhan ZHANG Kefeng DING(Department of Medical Oncology Department of Surgical Oncology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China)
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2017年第19期973-978,共6页
Chinese Journal of Clinical Oncology
基金
国家自然科学基金项目(编号:81272455
81472664)
中国国家卫生行业公益性基金项目(编号:201402015)
浙江省自然科学基金项目(编号:LY14H160019)
十二五国家科技支撑计划项目(编号:2014BAI09B07)资助~~
关键词
直肠癌
肺转移
多学科讨论
临床完全缓解
观察等待
局部治疗
维持治疗
rectal cancer
lung metastasis
multidisciplinary team（MDT）
clinical complete remission
watch-and-wait
local therapy
maintenance chemotherapy
