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感染可能性评分与降钙素原及C-反应蛋白在预测会阴侧切术后切口感染中的应用价值研究 被引量:7

Clinical value of infection probability score,procalcitonin and C-reactive protein in prediction of postoperative incision infection in patients undergoing lateral episiotomy
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摘要 目的探讨感染可能性评分(IPS)、降钙素原(PCT)、C-反应蛋白(CRP)在预测会阴侧切术后切口感染中的应用价值,为会阴侧切术后切口感染的防治提供参考。方法选取2016年1月-12月医院住院分娩的临产产妇200例,术前行IPS评分,测定血PCT与CRP,观察会阴侧切术后切口感染率,切口感染者采集局部分泌物行细菌培养。结果 200例产妇术后发生切口感染18例,感染率为9.00%,其中13例培养出病原菌,病原菌培养阳性率为72.22%,培养出病原菌13株,以大肠埃希菌7株为主,占53.85%;感染产妇IPS、PCT、CRP分别为(8.12±4.20)分、(0.06±0.03)ng/ml、(6.43±1.61)mg/L,高于非感染产妇的(5.10±2.41)分、(0.04±0.01)ng/ml、(5.19±0.97)mg/L,差异有统计学意义(P<0.05);术前IPS低风险与高风险产妇术后切口感染率分别为4.22%、32.35%,术前PCT阴性与阳性产妇术后切口感染率分别为2.78%、25.00%,术前CRP阴性与阳性患者术后切口感染率分别为4.76%、16.22%,差异有统计学意义(P<0.05)。结论会阴侧切术前IPS评分高、PCT和CRP阳性产妇术后发生切口感染的风险性明显增高,IPS、PCT和CRP用于预测会阴侧切术后切口感染具有一定临床价值。 OBJECTIVE To explore the clinical value of infection probability score(IPS),procalcitonin(PCT)and C-reactive protein(CRP)in prediction of postoperative incision infections in patients undergoing lateral episiotomy so as to provide guidance for prevention and treatment of the postoperative incision infections.METHODS A total of 200 parturient women who were hospitalized from Jan 2016 to Dec 2016 were enrolled in the study,the IPS of the study objects was analyzed,the blood PCT and CRP were determined,the incidence of postoperative incision infection was observed,and the local secretions specimens that were collected from the study objects with incision were cultured.RESULTS Of the 200 parturient women,18 had postoperative incision infections,with the infection rate 9.00%,of whom 13 were cultured positive for pathogens,with the positive rate of culture of pathogens 72.22%.Totally 13 strains of pathogens were isolated,of which 7(53.85%)were Escherichia coli.The IPS,PCT and CRP of the parturient women with infections were respectively(8.12±4.20)points,(0.06±0.03)ng/ml and(6.43±1.61)mg/L,higher than(5.10±2.41)points,(0.04±0.01)ng/ml and(5.19±0.97)mg/L of the parturient women without infection,and there was significant difference(P〈0.05).The incidence of postoperative incision infections was 4.22% in the parturient women at low risk of preoperative IPS,32.35% in the parturient women at high risk of preoperative IPS;the incidence of postoperative incision infections was 2.78% in the parturient women with negative preoperative PCT,25.00% in the parturient women with positive preoperative PCT;the incidence of postoperative incision infections was 4.76% in the parturient women with negative preoperative CRP,16.22% in the parturient women with positive preoperative CRP,and there was significant difference(P〈0.05).CONCLUSION The risk of postoperative incision infection is remarkably increased in the parturient women with high IPS,PCT and CRP before the lateral episiot
作者 简萍 胡秋燕 李钟艳 胡薇 朱圆 JIAN Ping HU Qiu-yan LI Zhong-yan HU Wei ZHU Yuan(Southwest Guizhou Vocational and Technical College, Xingyi, Guizhou 562400, Chin)
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2017年第20期4764-4767,共4页 Chinese Journal of Nosocomiology
关键词 切口感染 会阴侧切术 感染可能性评分 降钙素原 C-反应蛋白 Incision infection Lateral episiotomyl Infection probability score Procalcitonin C-reactive protein
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