摘要
目的观察右美托咪定复合丙泊酚在无痛胃镜下行食管扩张术与食管支架置入术的安全性和有效性。方法食管扩张术和食管支架置入术患者50例,分为丙泊酚组(A组)25人、右美托咪定复合丙泊酚组(B组)25人。A组采用丙泊酚静脉全身麻醉,B组采用右美托咪定复合丙泊酚静脉全身麻醉。两组均记录术前、胃镜经过声门时、术中、术毕时的收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(Sp O2),同时记录操作过程中患者吞咽、呛咳及体动的发生次数及内镜医师对两组患者镜下视野及蠕动情况的满意度。结果 A组患者胃镜经过声门及术中引起心率增加,血压明显上升,与术前比较差异有统计学意义(P<0.05),而B组患者上升不明显,与术前相比差异无统计学意义(P>0.05),与A组相比,差异有统计学意义(P<0.05);B组患者术中吞咽、呛咳、体动很少出现,较A组明显减少(P<0.01);B组患者医生满意度高于A组,但差异无统计学意义(P>0.05)。结论右美托咪定复合丙泊酚静脉全身麻醉可安全有效地应用于无痛胃镜下的食管扩张术与食管支架置入术,且优于单纯使用丙泊酚静脉麻醉。
【Objective】To observe the safety and efficacy of dexmedetomidine combined with propofol in esophageal dilation and esophageal stent placement.【Methods】Fifty patients underwent esophageal dilation and esophageal stent placement were divided into propofol group（group A） and dexmedetomidine combined with propofol group（group B）, with 25 cases in each group. Group A was given general anaesthesia with propofol, and group B was given general anaesthesia of dexmedetomidine combined with propofol. Before operation, when the gastroscope passed through the glottis, during operation and after operation, systolic blood pressure（SBP）, diastolic blood pressure（DBP）, heart rate（HR） and blood oxygen saturation（Sp O2） in the two groups were recorded. At the same time the frequency of swallowing, choking cough and body movement in the process of operation was recorded, and the satisfaction of endoscopic physicians for microscopic vision and peristalsis of patients in the two groups was observed.【Results】When the gastroscope passed through the glottis and during the operation, heart rate of patients in group A increased, blood pressure rised obviously, and there were statistically significant differences compared with the preoperative ones（P〈0.05）, while the rise in group B patients was not obvious, there was no statistically significant difference compared with the preoperative ones（P〉0.05）, but there were statistically significant differences in heart rate and blood pressure between the two groups（P〈0.05）. There were fewer cases of swallowing, coughing, and body movement in group B than in group A（P〈0.01）. The physician satisfaction in group B was higher than that in group A, but the difference was not statistically significant（P〉0.05）.【Conclusion】 Intravenous general anesthesia of dexmedetomidine combined with propofol can be safely and effectively used in esophageal dilatation and esophageal stent placement under painless gastroscopy, and is superior to the s
作者
姚宇
刘晓波
王保华
王凤娟
YAO Yu LIU Xiaobo WANG Baohua WANG Fengjuan(Anesthesiology Department, Hospital Attached to Changchun University of Chinese Medicine, JiLin, Changchun 130021, China)
出处
《中国医学工程》
2017年第9期32-34,共3页
China Medical Engineering
