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凉山彝族妇女妊娠期低T4血症对妊娠结局的影响

Influence of low T4 during pregnancy on the outcome of pregnancy in Liangshan Yi nationality women
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摘要 目的探讨凉山彝族妊娠期低T4血症对妊娠结局的影响。方法以2015年9月~2017年2月在我院就诊及妊娠期保健的746例凉山彝族自治州各县彝族女性为研究对象,采用化学发光酶免疫方法检测促甲状腺素(TSH),游离甲状腺素(FT4),甲状腺过氧化物酶抗体(TPOAb),分析凉山彝族妊娠低T4血症对妊娠结局的影响。评价低T4血症对凉山彝族妊娠结局的重要性。结果低T4血症与正常组比较,自然流产发生率、新生儿出生时Apgar评分比较差异具有统计学意义(P<0.05),FT4越低,差异越有统计学意义(P<0.01),更易导致妊娠不良结局的发生。结论对妊娠期单纯低FT4彝族孕妇给予早期干预是必要的,可避免妊娠不良结局的发生。 Objective To explore the influence of low T4 during pregnancy on the outcome of pregnancy in Liangshan Yi nationality women. Methods From September 2015 to February 2017, 746 Yi nationality women of each county in Liangshan Yi Autonomous Prefecture were studied, the chemiluminescent enzyme immunoassay was used to detect thyroid-stimulating hormone (TSH), free thyroxine (FT4) and thyroid peroxidase antibody (TPOAb), the effects of low T4 in Liangshan Yi Nationality on pregnancy outcome was analyzed. The importance of low T4 on the outcome of the pregnancy in Liangshan Yi Nationality was evaluated. Results The incidence of spontaneous abortion and Neonatal Apgar score at birth of low T4 patients compared with normal group, the differences statistically significant (P 〈 0.05), FT4 was lower, the more significant difference (P 〈 0.01), and more likely to lead to the occurrence of adverse pregnancy outcomes. Conclusion It is necessary to give early intervention to pregnant women with simple low FT4 Yi in pregnancy, so as to avoid the adverse pregnancy outcomes.
出处 《中国医药科学》 2017年第19期9-11,19,共4页 China Medicine And Pharmacy
基金 四川省凉山州学术和技术带头人培养基金(凉人社办发﹝2015﹞170号)
关键词 凉山彝族 妊娠期 低T4血症 妊娠不良结局 Liangshan Yi nationality Pregnancy Low T4 Bad perinatal outcomes
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