摘要
妊娠期由于其特殊的生理过程甲状腺各项指标的变化很大,妊娠期甲状腺激素的产生、循环、代谢、调节以及甲状腺免疫均会随妊娠的不同阶段而改变。甲状腺激素是胎儿脑神经发育的必需激素,甲状腺激素缺乏严重影响胎儿的脑发育,近年来妊娠期甲状腺功能异常的发病率明显升高,可导致母儿不良妊娠结局。综述近年来关于妊娠期母体及胎儿甲状腺功能变化、相关母体甲状腺疾病发病情况及对胎儿的影响,旨在促进正确诊断妊娠期甲状腺疾病,合理保护妊娠期甲状腺功能,预防妊娠期甲状腺功能异常带来的一系列产科并发症及不良妊娠结局,避免新生儿远期生存质量的影响。
Due to the large changes in specific physiological indicators of thyroid during pregnancy, the gestational thyroid hormone production, circulation, metabolism, regulating and immunity will change according to the different stages of pregnancy. Thyroid hormone is essential for fetal brain development, the deficiency of it seriously affect fetal brain development,in recent years, the incidence of gestational thyroid dysfunction increased significantly, it can lead to adverse pregnancy outcomes. This article reviews the changes of thyroid function on pregnant women and fetus, as well as the incidence of thyroid disorders in pregnant women and the adverse effects on their fetus. The correct diagnosis of thyroid disease and reasonable protection designed to prevent thyroid dysfunction during pregnancy from bringing a series of obstetric complications, and adverse pregnancy outcomes, to avoid affecting the quality of long-term survival of the newborn.
出处
《国际妇产科学杂志》
CAS
2015年第3期330-334,共5页
Journal of International Obstetrics and Gynecology