摘要
维生素B_(12)(vitamin B_(12),Vit B_(12))是机体不可或缺的微量营养素,因人体不能主动合成,需从食物中摄取,而胃部的消化环节对Vit B_(12)的后续吸收至关重要。幽门螺杆菌(helicobacter pylori,HP)是一种能定植于胃内的致病菌,长期感染可导致各种类型的胃部疾病,且HP感染与Vit B_(12)缺乏密切相关。本文从Vit B_(12)概述、HP感染和HP根除治疗对血清Vit B_(12)的影响及可能存在的相关机制等方面对Vit B_(12)与HP关系的研究进展进行综述。
Vitamin B_(12)(Vit B_(12))is an indispensable micronutrient.Humans are unable to synthesize Vit B_(12) and thus rely on dietary intakes.Digestive processes occurred in the stomach is crucial to the subsequent absorption of Vit B_(12).Helicobacter pylori(HP),the pathogenic bacteria colonizing the stomach,can lead to various gastric diseases.The HP infection is closely related to Vit B_(12) deficiency.This paper reviews the relationship between Vit B_(12) and HP from the aspects of Vit B_(12) overview,HP infection,and effect of eradication therapy on serum Vit B_(12) and its possible mechanisms.
作者
陈淑平(综述)
谢勇(审校)
CHEN Shu-ping XIE Yong(Department of Gastroenterology, the First Affiliated Hospital of Nanchang University ,Gastroenterology Institute of Jiangxi Province,Key Laboratory of Digestive Diseases of Jiangxi Province, Nanchang 330006, Chin)
出处
《南昌大学学报(医学版)》
CAS
2017年第4期84-87,共4页
Journal of Nanchang University:Medical Sciences
基金
国家自然科学基金(81260076)