摘要
脂肪代谢异常与机体代谢性疾病和炎症反应的发生和发展密切相关,可引起全身多脏器功能障碍。传统的脂肪组织检查方法多为有创性检查,多模态MRI技术能够对脂肪组织的功能以及异位脂质沉积进行全面的评估,可为脂肪相关代谢性疾病的诊断、疾病进展监测和治疗效果的评价提供大量信息。就多模态MRI技术在定量评价脂肪组织和脂肪肝中的技术进展与研究现状进行综述。
Abnormal fat metabolism plays an important role in the initiation and development of systemic metabolic diseases and inflammation response, which can lead to multiple organ dysfunction. Traditional methods for analyzing adipose tissue（AT） are all invasive approaches. Multimodal magnetic resonance imaging（MRI） can provide a comprehensive assessment of the function of AT, ectopic fat deposition, and can provide abundant information for diagnosis, monitoring disease progression, and evaluation of therapeutic efficacy of metabolic diseases. This article aimed to review technological advances and research application of multimodal MRI in quantitative evaluation of fat tissue and fatty liver.
出处
《国际医学放射学杂志》
2017年第5期561-564,569,共5页
International Journal of Medical Radiology
基金
天津市重点实验室开放基金重点项目(TJC1403)
关键词
脂肪定量
水脂分离
脂肪肝
磁共振成像
扩散加权成像
血氧水平依赖
磁共振波谱成像
Fat quantification
Water-fat separation
Fatty liver
Magnetic resonance imaging
Diffusion-weighted imaging
Blood oxygen level-dependent
Magnetic resonance spectroscopy
