摘要
维生素D是维持人体健康的重要营养素之一。新近研究发现,维生素D不仅参与人体钙磷代谢,还可通过抗氧化应激、调节细胞增殖分化及细胞凋亡等多种非经典途径或替代途径参与机体代谢及免疫调节,与内分泌、自身免疫及肿瘤等均有密切关系。该文对维生素D与肥胖、糖尿病、生长激素及胰岛素样生长因子-1、甲状腺疾病、肾上腺疾病及甲状旁腺功能亢进等的关系加以阐述。
Vitamin D is one of the most important nutrients to maintain human health. Recent studies have found that vita- min D is not only involved in the calcium and phosphorus metabolism, but also, through antioxidant stress, regulates cell proliferation and differentiation, apoptosis, and through other non-classical pathways or alternative ways, participates in the metabolism and immune regulation, and is closely related to endocrine, autoimmune and tumors. This article reviews the relationship between vitamin D and endocrine diseases including obesity, diabetes, growth hormone/nsulin-like growth factor- 1, thyroid disease, adrenal disease and hyperparathyroidism.
出处
《中国实用儿科杂志》
CSCD
北大核心
2017年第9期673-679,共7页
Chinese Journal of Practical Pediatrics
关键词
维生素D
代谢
机制
维生素D受体
激素
vitamin D
metabolism
mechanism
vitamin D receptor
hormone
