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不同剂量阿托伐他汀对大脑中动脉狭窄进展的影响 被引量:1

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摘要 目的:研究不同剂量阿托伐他汀对大脑中动脉狭窄进展的影响。方法:选取2014年8月~2015年10月许昌市人民医院治疗大脑中动脉狭窄患者102例,随机数字表法分组,各51例。对照组予以低剂量(10mg/d)阿托伐他汀,观察组予以高剂量(40mg/d)阿托伐他汀治疗。统计对比两组临床疗效及治疗前后血脂指标[总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)]水平。结果:治疗后两组临床总有效率比较,观察组88.24%(45/51)高于对照组的72.55%(37/51),差异具有统计学意义(P<0.05);治疗后观察组TC、TG及LDL-C均低于对照组,差异具有统计学意义(P<0.05)。结论:大脑中动脉狭窄采用高剂量阿托伐他汀治疗,相比低剂量,可提高临床疗效,并降低血脂水平。
作者 信香兰
出处 《北方药学》 2017年第9期66-67,共2页 Journal of North Pharmacy
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