摘要
目的研究脑血管储备功能在伴大脑中动脉狭窄的急性缺血性卒中后认知障碍的动态变化。方法对正常对照组及伴大脑中动脉狭窄的急性缺血性卒中后认知障碍患者进行MMSE量表评分,应用经颅多普勒进行脑血管储备功能检测,3个月后复查上述指标。结果急性卒中后认知障碍患者(MCASCI组)屏气指数(BHI)及Vm上升率(%)明显降低(P<0.01),3个月后MCASCI组患者MMSE、屏气指数(BHI)及Vm上升率有所好转,较正常对照组仍有明显降低(P<0.01),但与0个月时相比有所改善(P<0.01)。结论伴大脑中动脉狭窄的急性卒中后认知障碍患者在3个月后认知功能及脑血管储备能力均有所好转,脑血管储备功能恢复与急性缺血性卒中后认知障碍预后密切相关。
Objective To study the dynamic changes of cerebrovascular reserve in cognitive impairment with middle cerebral artery stenosis after acute ischemic stoke. Methods The MMSE score of the control group and group of cognitive impairment with middle cerebral artery stenosis（MCASCI）after acute ischemic stroke was graded,and cerebrovascular reserve was detected by transcranial Doppler,MMSE and CVR were reviewed 3 months later. Results BHI and Vm% of the group of MCASCI were decreased （P〈0.01） ,MMS,BHI and Vm % the group of MCASCI increased （P 〈0.01） 3 months later. Compared with the control group, there were obviously decreased（P〈0.01）. But compared with 0 months,there were improved （P〈0.01）. Conclusion Cognitive function and eerebrovascular reserve in cognitive impairment with middle cerebral artery stenosis after acute ischemic stoke reserve were improved 3 months later. The recovery of cerebrovascular reserve is closely related to the prognosis of cognitive impairment after acute ischemic stroke.
作者
张馨
李丽
李淞
ZHANG Xin LI Li LI Song.(Department of Neurology, The People ＇ s Hospital of Jilin Province, Changchun 130021 ,China)
出处
《中国实验诊断学》
2017年第9期1520-1522,共3页
Chinese Journal of Laboratory Diagnosis
基金
吉林省科技厅重点科技攻关项目(20150204094SF)
关键词
急性缺血性卒中后认知障碍
大脑中动脉狭窄
脑血管储备功能
cognitive impairment after acute ischemic stoke
the middle cerebral artery stenosis
cerebrovascular reserve
