摘要
目的探讨泮托拉唑与根除幽门螺杆菌治疗对服用阿司匹林老年患者胃及十二指肠损伤的预防作用。方法选择2015年1月至2016年12月在本院接受阿司匹林服用治疗的老年患者作为研究对象,共30例,通过数字编号和抽取表法将患者分为两组,其中对观察组患者采用洋托拉唑维持治疗,对照组患者采用根除幽门螺旋菌治疗,对两组患者胃及十二指肠损伤情况及幽门螺杆菌清除情况进行比较分析。结果在经过治疗后,观察组患者胃及十二指肠黏膜损伤严重程度显著低于对照组,0分和1分显著高于对照组,数据比较差异具有统计学意义(P<0.05);观察组患者幽门螺杆菌清清除率为93.33%,对照组患者幽门螺杆菌清除率为46.67%,数据比较差异具有统计学意义(P<0.05)。结论对长期服用阿司匹林治疗的老年患者进行洋托拉唑维持治疗能够有效预防其胃及十二指肠损伤情况的发生,进一步根除幽门螺杆菌,有利于改善患者病情。
Objective To investigate the effects of pantoprazole and Helicobacter pylori eradication therapy on the preventive effect of aspirin in elderly patients with gastric and duodenal injury. Methods During the period from January 2015 to December 2016 in our hospital for treatment of elderly patients with aspirin as the research object, a total of 30 cases, the number and extraction table method were divided into one of the two groups, the observation group were treated with pantoprazole maintenance treatment, the control group was treated with eradication of Helicobacter pylori treatment, the two groups of patients with gastric and duodenal injury and Helicobacter pylori eradication situation were analyzed. Results After treatment, the observation group in patients with gastric and duodenal mucosa injury severity was significantly lower than the control group, 0 points and 1 points higher than that of the control group, with statistically significant data difference(P<0.05); the observation group of patients with Helicobacter pylori clearance clearance rate was 93.33%, the control group of patients with Helicobacter pylori eradication rate was 46.67%, with statistically significant difference data(P<0.05). Conclusion In elderly patients with long-term aspirin therapy of pantoprazole maintenance treatment can effectively prevent the occurrence of gastric and duodenal injury, further the eradication of Helicobacter pylori and to improve the patient's condition.
出处
《中国医药指南》
2017年第25期17-18,共2页
Guide of China Medicine
