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两种剂型的布洛芬在治疗儿童发热中的临床效果评价 被引量:5

Clinical Evaluation of Two Dosage Forms of Ibuprofen in the Treatment of Fever in Children
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摘要 目的探讨布洛芬两种剂型治疗儿童发热的临床效果评价。方法随机选取114例发热儿童的临床资料进行回顾性分析,并将其随机分为对照组(57例)和治疗组(57例),对照组给予布洛芬混悬液,治疗组给予布洛芬缓释混悬液,比较两组患者不良反应率和治疗总有效率。结果治疗组患者治疗总有效率(96.49%)与对照组(92.98%)比较,差异无统计学意义(P>0.05);治疗组患者不良反应率(7.02%)低于对照组(21.05%),对比差异具有统计学意义(P<0.05)。结论布洛芬两种剂型治疗儿童发热均具有较好的临床效果,但布洛芬缓释混悬液治疗儿童发热的不良反应低。 Objective Objective To evaluate the clinical efficacy of two dosage forms of ibuprofen in the treatment of fever in children. Methods The clinical data of 114 children with fever were retrospectively analyzed. The patients were randomly divided into the control group (57 cases) and the treatment group (57 cases), the control group was treated with ibuprofen suspension, and the treatment group was treated with ibuprofen sustained release suspension. The adverse reactions rate and the total effective rate of the two groups were compared. Results The total effective rate of treatment group patients (96.49%) and control group (84.21%) had little difference, the difference had no statistically significant (P 〉 0.05); adverse reaction rate (7.02%) in the patients in the treatment group was significantly lower than the control group (21.05%), the difference had statistical significant (P 〈 0.05). Conclusion Two dosage forms of ibuprofen have good clinical effects on fever in children, but the adverse reaction of ibuprofen sustained release suspension on fever in children is lower.
出处 《中国卫生标准管理》 2017年第20期100-101,共2页 China Health Standard Management
关键词 布洛芬 剂型 儿童发热 效果评价 bloven dosage children fever effect evaluation
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