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复方小儿退热栓治疗小儿高热惊厥的有效性及安全性分析

Analysis on effect and safety of compound pediatric antifebrile for treatment of children with febrile convulsion
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摘要 目的探讨复方小儿退热栓治疗小儿高热惊厥的有效性及安全性。方法将我院2016年5月~2017年5月收治的高热惊厥患儿80例为研究对象,按随机原则分为观察组和对照组各40例。对照组患儿采用常规抗感染治疗,包括地西泮注射液以及口服苯巴比妥;观察组患儿在对照组治疗的基础上给予复方小儿退热栓治疗。观察比较两组患儿的临床疗效及不良反应发生率。结果观察组患儿的治疗总有效率为95.00%,明显高于对照组的75.00%,两组比较差异有统计学意义(P<0.05)。观察组患儿的不良反应发生率为2.50%,对照组为30.00%,两组比较差异有明显统计学意义(P<0.05)。结论在常规抗感染治疗的同时应用复方小儿退热栓治疗高热惊厥患儿的临床疗效显著,能有效降低不良反应发生率,值得临床推广应用。 Objective To investigate the efficacy and safety of compound pediatric antifebrile suppository for treatment of the children with febrile convulsion. Methods 80 cases with febrile convulsion from May 2016 to May 2017,according to the principle of random divided into observation group and control group(each n=40).The control group was used conventional anti-infective therapy,including diazepam injection and oral phenobarbital;Observation group was basis on the control group given compound pediatric antifebrile.The clinical efficacy and the incidence of adverse reactions in two groups were compared. Results The total effective rate of observation group was 95.00%,significantly higher than the 75.00%in the control group(P<0.05).Observation group with the incidence of adverse reactions was 2.50%,and the control group was 30.00%.Comparing the two groups has a significant statistical significance(P<0.05). Conclusion Based on the treatment of conventional anti-infection and application of compound of pediatric antifebrile suppository for the children with febrile convulsion the curative effect is significantly,can effectively reduce the incidence of adverse reactions.
作者 曲春霞 QU Chun-xia(Pediatric department,people's hospital of Tanghe county,Tanghe,Henan,473400,China)
出处 《蛇志》 2018年第1期64-65,86,共3页 Journal of Snake
关键词 复方小儿退热栓 儿童 高热惊厥 治疗效果 Compound pediatric antifebrile suppository Children Febrile convulsion Curative effect
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