摘要
目的观察依托咪酯与丙泊酚的联合应用在无痛人工流产麻醉中的临床疗效及安全性。方法收集我院2015年3月至2016年3月入院的80例无痛人工流产患者,随机分为两组,对照组患者采取丙泊酚+舒芬太尼麻醉,实验组患者采取依托咪酯+丙泊酚+舒芬太尼麻醉,比较两组患者各时间点临床指标、麻醉相关指标与手术事件、不良反应的相关性。结果两组患者麻醉期间各时间点SpO_2、MAP与HR水平无显著差异(P>0.05);实验组患者苏醒时间与行动恢复时间显著低于对照组(P<0.01);实验组患者注射痛与总体不良反应发生率显著低于对照组(P<0.05)。结论依托咪酯与丙泊酚的联合应用在无痛人工流产麻醉中的临床效果显著,具有恢复更快、不良反应更少的特点。
Objective To observe the clinical efficacy and safety of etomidate combined with propofol in painless abortion anesthesia. Method 80 patients with painless induced abortion admitted from March, 2015 to March, 2016 were randomly divided into two groups. The patients in the control group were treated with propofol ＋ sufentanil anesthesia. The patients in the experimental group were treated with etomidate ＋ propofol and sufentanil. The correlation of clinical indexes, anesthesia related indexes, surgical events and adverse reactions were compared between the two groups. Result There were no significant differences in SpO2, MAP and HR between the two groups （P〉 0.05）. The recovery time and recovery time of the patients in the experimental group were significantly lower than those in the control group （P 〈0.01）. The incidence of injection pain and overall adverse reaction in the experimental group was significantly lower than that in the control group （P 〈0.05）. Conclusion The combination ofetomidate and propofol has obvious clinical effect in painless induced abortion. It has the characteristics of quicker recovery and fewer adverse reactions.
出处
《中国药物警戒》
2017年第8期457-459,共3页
Chinese Journal of Pharmacovigilance
