摘要
目的利用皮肤镜观察黄金微针联合水光注射疗法并外用重组牛碱性成纤维细胞生长因子(rbbFGF)在面部年轻化作用中的疗效。方法纳入面部肌肤自然老化患者20例女性,年龄30~55岁,先给予多源射频治疗仪黄金微针注射注射至真皮层,能量范围13~16 W,水光注射仪注射用无交联透明质酸注射至真皮浅层,使用剂量2mL,治疗后连续每天使用rb-bFGF,根据皮肤治疗后干燥情况1天3~5次,共7d。每次治疗后借助JEDA皮肤镜进行观察,临床医生根据色斑、皱纹、肌肤纹理、毛孔等综合评估治疗效果,同时患者行自我满意度量表评估。结果患者经过两次相控微针结合水光注射治疗并使用rb-bFGF后,面部轮廓紧实,肤质改善明显,皮肤镜客观评价皮肤细腻程度、皮肤纹理,皮肤水分情况改善明显,主观满意程度较高。结论黄金微针联合水光注射治疗并外用rb-bFGF,为面部年轻化提供了较好的联合治疗方案。
Objective To explore the dermoscopic changes facial rejuvenation after the combination therapy of gold microacupuncture, Hyaluronic acid （HA） injection, and recombinant bovine alkaline fibroblast growth factor （rb-bFGF）. Methods Twenty cases of patients （age from 30 to 55 year-old） with facial skin naturally aging were included. The patients received multi-source radio frequency therapeutic apparatus for injection at the subbermal- dermal levels from 13-16 W. Non-cross-linking HA of 2 mL was injected in the upper dermis, rb-bFGF was externally applied 3 to 5 times a day for a week according to the dry skin issues, human-like collagen mask was applied once a day for a week. Dermoscopy was used to observe the changes of skin, such as olor spot, wrinkle, skin texture and pore. Results The patients were found facial contour tighten, skin quality improved obviously after two phase combination therapy, the objective evaluation of dermoscopy delicated skin mirror, skin texture, skin moisture condition improved obviously, while the subjective satisfaction degree was increased. Conclusion Golden microacupuncture combined with HA injection and rb-bFGF could provide better joint treatment for facial rejuvenation.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2017年第5期792-795,共4页
Journal of Sichuan University(Medical Sciences)
