摘要
目的观察五苓散联合补阳还五汤对创伤性脑水肿病人脑部供血及预后的影响。方法选取2013年9月—2015年9月在我院住院治疗的创伤性脑水肿病人40例,按入院前后顺序随机分为试验组与对照组,各20例。组使用西医保守治疗,以20%甘露行脱水。试验组在对照组基础上,选用五苓散联合补阳还五汤治疗,以10d为1个疗程,3个疗程后检测并比较病人治疗前后左右大脑前动脉(ACA)、中动脉(MCA)、后动脉(PCA)的平均血流速度(Vm)、阻力指数(RI)及临床功能评分(KPS)。结果治疗后,两组病人各动脉Vm均较治疗前有所提高,RI均较治疗前有所降低(P<0.05);且治疗后试验组较对照组Vm提高及RI降低得更明显,差异有统计学意义(P<0.05)。试验组治疗后临床功能评分明显好于对照组,差异有统计学意义(P<0.05)。结论五苓散联合补阳还五汤可明显降低创伤性脑水肿病人的脑血流阻力,改善病人脑部供血,从而减轻脑水肿引起的脑损害,改善病人的预后。
Objective To observe the influence of Wuling power（WLP）and Buyang Huanwu decoction（BYD）on the cerebral blood flow and prognosis in patients with traumatic brain edema.Methods Forty patients with traumatic brain edema from September2013 to September 2015 were randomly divided into two groups：control group（n =20）treated with routine treatment,and treatment group（n =20）treated with WLP and BYD in the basis of routine treatment for 3 courses of treatment,10 days as a course of treatment.The mean velocity（Vm）,and resistent index（RI）of anterior cerebral artery（ACA）,middle cerebral artery（MCA）and posterior cerebral artery（PCA）,and karnofsky performance status（KPS）were observed.Results After treatment,the Vm of ACA,MCA and PCA in two groups was higher than that before treatment,which was higher in treatment group than that in control group（P〈0.05）.The RI of ACA,MCA and PCA in two groups was lower than that before treatment,which was lower in treatment group than that in control group（P〈0.05）.The KPS score in treatment group was better than that in control group（P〈0.05）.Conclusion WLP and BYD can significantly reduce the cerebral blood flow resistance and improve the brain blood supply,alleviate the damage of brain edema,and improve the prognosis in patients with traumatic brain edema.
出处
《中西医结合心脑血管病杂志》
2017年第17期2104-2106,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
创伤性脑水肿
五苓散
补阳还五汤
颅脑血流动力学
traumatic brain edema
Wuling power
Buyang Huanwu decoction
cerebral hemodynamics
