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喷他佐辛鼻腔给药用于全麻剖宫产对母婴的影响 被引量:1

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摘要 目的评价喷他佐辛鼻腔给药用于全麻剖宫产对母婴的影响。方法择期全麻下剖宫产术患者120例,年龄22~32岁,体质量50~75kg,ASA分级I或Ⅱ级,采用随机数字表法分为两组:喷他佐辛组(观察组,n=60)和生理盐水组(对照组,n=60)。观察组麻醉诱导前30min鼻腔给予喷他佐辛0.5mg/kg 2mL,每侧鼻腔各1mL;对照组鼻腔给予等容量生理盐水。分别于麻醉诱导期、麻醉维持期和麻醉恢复期记录产妇的收缩压(SBP)、舒张压(DBP)、心率(HR)的最高值和最低值。分别记录新生儿1min和5min的Apgar评分。结果与对照组比较,观察组产妇于麻醉诱导期、麻醉维持期和麻醉恢复期的收缩压最高值(SBPmax)、舒张压最高值(DBPmax)降低,心率最高值(HRmax)降低(P<0.05),两组产妇SpO2及新生儿Apgar评分比较,差异均无统计学意义(P>0.05)。结论喷他佐辛鼻腔给药用于全麻剖宫产患者,产妇血流动力学更平稳,对新生儿无影响。
出处 《福建医药杂志》 CAS 2017年第4期118-120,共3页 Fujian Medical Journal
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