摘要
目的:通过对某院抗菌药物使用情况与细菌耐药性的研究分析,为抗菌药物的合理使用提供技术支持。方法:调取某院2015年抗菌药物使用量,计算用药频度(DDDs),结合全年住院患者细菌分离及耐药资料进行统计,分析病原菌对抗菌药物的耐药情况。结果:2015年某院抗菌药物DDDs排序中,第三代头孢菌素使用频度最高,同期分离的病原菌以大肠埃希菌检出率最多。结论:第三代头孢菌素类抗菌药物在某院存在不合理使用,医院应进一步加强抗菌药物的规范化管理,尽可能的减少细菌耐药的发生率。
Objective：Through the analysis of antimicrobial drug use and drug resistance of bacteria in a hospital, technical support for the rational use of antimicrobia] drugs is provided.Methods： The amount of antibacterial drug use from a hospital in 2015, calculate the frequency of drug use （DDDs）, with the annual hospitalization in patients with bacterial isolation and drug resistance data for statistical analysis, the antimicrobia] resistance of the pathogen of a hospital in 2015.Results： The antibacterial drugs DDDs ranking, the third generation cephalosporins use the highest frequency of the same period, pathogen separation in Escherichia coll. Conclusion： the detection rate of up to third generation cephalosporin antibiotics in a hospital is not reasonable use of medicine. The hospital should further strengthen the standardized management of antibacterial drugs, and reduce the incidence of bacterial resistance as much as possible.
出处
《安徽卫生职业技术学院学报》
2017年第4期7-9,共3页
Journal of Anhui Health Vocational & Technical College
关键词
抗菌药物
用药频度
耐药性
Antibacterial drugs
DDDs
Drug resistance
