摘要
目的 :运用中医传承辅助系统总结王春生老师治疗慢性胃炎的用药规律。方法 :通过回顾性整理、收集2013年10月~2014年10月王春生在专家门诊诊治的慢性胃炎病例202例,将全部四诊及处方用药信息录入数据库,采用中医传承辅助平台V2.5进行数据分析。结果:202例患者共使用108味药物,其中使用频次在前5位的分别为茯苓198次,炒白术185次,白蔻174次,砂仁147次,木香135次。基于关联规则apriori算法的组方规律分析,选取支持度40%、置信度>95%的药物组合,有9味药:炒白术、茯苓、白蔻、壳砂仁、厚朴、法半夏、黄连、生薏苡仁、木香;将支持度提升至50%,有6味药物:炒白术、茯苓、白蔻、壳砂仁、厚朴、木香。通过熵聚类和改进的互信息法可以挖掘得到潜在的药物组合,基于无监督熵层次聚类根据潜在核心组合得出新处方。结论:慢性胃炎的基本病因为饮食不节与情志不畅两方面,虚为本病的主要病机,湿为本病的主要病理因素,食、瘀、毒为次要病理因素,脾、胃、肝为本病的主要病位,以痞满、胃脘痛为主要不适。
Objective ：To summarize Professor WANG＇s experience in the treatment of chronic gastritis by traditional Chinese medicine（TCM） Inheritance Support System and to find out prescription law. Methods：There were 202 cases of chronic gastritis from Professor WANG＇s clinic from October 2013 to October 2014. All the diagnosis information and prescription were input into the database and analyzed with TCM inheritance Support Platform（Version 2.5）. Results：There were 108 herbs prescribed in 202 patients,and the herbs of the highest frequency were Fuling （ 198 ）, Chaobaizhu （ 185 ）, Baikou （174）, Qiaosharen （ 147 ） and Muxiang （ 135 ）. Based on the linkage law and aprior method,with support degree 40%,confidence interval 95%,9 herbs were determined,including Chaobaizhu,Fuling,Baikou,Qiaosharen,Houpu,Fabanxia,Huanglian,Shengyiyiren and Muxiang,with support degree 50% ,6 herbs were determined：Chaobaizhu,Fuling,Baikou,Qiaosharen,Houpu and Muxiang. Through entropy clustering and improvement of mutual information,the potential herbal combination were obtained. Through no supervised entropy cluster and potential combination,the core formula was deter- mined. Conclusion：The basic disease mechanism of chronic gastritis is improper diet and unhappiness in which deficiency is the major cause and dampness is the major pathological factors. And food,stasis and toxin are the secondary pathological factors. Spleen,stomach and liver are the major disease location,with distention,fullness ,and stomachache as the major symptoms.
出处
《山东中医杂志》
2017年第8期678-682,共5页
Shandong Journal of Traditional Chinese Medicine
关键词
王春生
慢性胃炎
数据挖掘
组方用药规律
WANG Chunsheng
chronic gastritis
data mining
prescription law
