摘要
目的综合分析职业性噪声接触对我国女工生殖功能的影响。方法采用文献计量学法,通过中国知网、万方数据库、中国生物医学文献数据库和中国科技期刊数据库,检索、收集、筛选1985—2016年发表在国内学术期刊上关于职业性噪声接触与作业女工生殖功能关系研究的文献,采用Rev Man 5.2软件对入选文献进行数据合并分析,计算合并比值比(OR)及其95%可信区间(CI)。结果共纳入25篇文献。与对照组比较,职业性噪声接触与女工月经周期异常(OR=2.26,95%CI:1.70~3.01)、痛经(OR=2.21,95%CI:1.78~2.75)、经期异常(OR=2.11,95%CI:1.40~3.18)、经量异常(OR=1.73,95%CI:1.34~2.23)、妊娠高血压(OR=1.82,95%CI:1.49~2.22)、妊娠贫血(OR=1.71,95%CI:1.25~2.34)、先兆流产(OR=1.98,95%CI:1.23~3.20)、自然流产(OR=1.76,95%CI:1.49~2.08)、死胎死产(OR=1.61,95%CI:1.22~2.13)、早产(OR=1.57,95%CI:1.36~1.81)和女工子代的低出生体质量(OR=1.66,95%CI:1.39~1.98)、先天畸形(OR=1.58,95%CI:1.10~2.27)的关联性均有统计学意义(P<0.01);噪声接触强度与上述敏感指标存在剂量-反应关系。与对照组比较,职业性噪声接触与女工过期产(OR=1.32,95%CI:0.81~2.15)的关联性无统计学意义(P>0.05)。结论职业性噪声接触可影响女工的生殖功能和妊娠结局;孕妇不应从事噪声作业。
Objective To analyze the effect of occupational noise exposure on reproductive function in Chinese female workers. Methods The published literatures that showed the relationship between occupational noise exposure and female workers＇ reproductive function from Chinese National Knowledge Infrastructure, Wanfang Data, Chinese Biology Medicine Database and China Science and Technology Periodical Database from 1985 to 2016 were collected, screened and analyzed using bibliometric method. The RevMan 5.2 software was used to calculate the pooled odds ratio （OR） and the 95% confidence interval （CI）. Results A total of 25 original research papers were included. The occupational exposure to noise was significantly associated with abnormality of female menstrual cycle （ OR = 2.26, 95% CI： 1.70-3.01 ）, dysmenorrheal （ OR =2. 21,95% CI： 1.78-2. 75）, abnormal menstrual period （ OR =2. 11,95% CI： 1.40-3. 18）, abnormal menstrual blood volume （ OR = 1.73, 95% CI： 1.34-2. 23）, pregnancy-induced hypertension （ OR = 1.82, 95% CI： 1.49- 2.22） , anemia in pregnancy （ OR = 1.71, 95% CI： 1.25-2. 34） , threatened abortion （ OR = 1.98, 95% CI： 1.23- 3.20）, spontaneous abortion （OR = 1.76, 95% CI： 1.49-2.08）, stillbirths （OR = 1.61, 95% CI： 1.22-2.13）, premature birth （ OR -- 1.57, 95% CI： 1.36-1.81 ）, neonatal low birth weight （ OR = 1.66, 95% CI： 1.39-1.98）, and congenital malformations （OR = 1.58, 95% CI： 1.10-2. 27） compared with the controls （P 〈 0. 01 ）. There was a dose- response relationship between the above-mentioned indicators and the intensity of noise exposure. Occupational noise exposure was not associated with over-term birth （ OR = 1.32, 95% CI： 0. 81-2. 15, P 〉 0. 05 ） compared with the controls. Conclusion Occupational noise exposure can affect the reproductive function and pregnancy outcomes of female workers. It is suggested that pregnant women should not be engaged in noise operations.
出处
《中国职业医学》
CAS
北大核心
2017年第4期430-435,共6页
China Occupational Medicine
基金
国家自然科学基金(81470146)
广州市民生科技重大项目(2014Y2-00067)
广州市医学重点学科建设项目
广州市职业环境与健康效应重点实验室建设项目(2014SY000020)
关键词
噪声
女工
生殖功能
META分析
Female workers
Reproductive function
Meta-analysis
