摘要
目的 观察中药薏苡附子败酱散治疗脾肾阳虚型溃疡性结肠炎（UC）的临床疗效.方法 选择2012年1月至2015年12月天津中医药大学第一附属医院收治的80例UC患者,按随机数字表法分为对照组和中西医结合治疗组,每组40例.对照组采用生理盐水100 mL加地塞米松10 mg灌肠,中西医结合治疗组用薏苡附子败酱散100 mL（薏苡仁30 g、制附子6 g、败酱草15 g、白芍15 g、制乳香6 g、制没药6 g、生甘草6 g）联合地塞米松10 mg灌肠,两组均以10 d为1个疗程,共3个疗程后观察临床疗效.比较两组治疗前后红细胞沉降率（ESR）和便常规红细胞（RBC）以及白细胞（WBC）阳性患者数的差异,并观察临床疗效.结果 两组治疗后ESR均较治疗前降低,便常规中RBC和WBC阳性例数均较治疗前减少,且以中西医结合治疗组的变化较对照组更显著〔ESR（mm/1 h）：15.00±3.07比20.55±3.87,便常规中RBC阳性患者数：7例比21例,便常规中WBC阳性患者数：14例比21例,均P〈0.05〕.中西医结合治疗组治疗总有效率明显高于对照组〔92.5%（37/40）比75.0%（30/40）,P〈0.05〕.结论 中药附子薏苡败酱散联合地塞米松灌肠对脾肾阳虚型UC的临床疗效优于仅应用激素治疗,且薏苡附子败酱散联合激素灌肠操作方法简便,疗效肯定.
Objective To observe the clinical effects of Yiyi Fuzi Baijiang powder for treatment of patients with ulcerative colitis （UC） accompanied by yang-deficiency of spleen and kidney.Methods Eighty patients with UC admitted to the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine （TCM） from January 2012 to December 2015 were enrolled, and they were divided into an integrated TCM and western medicine group （combined group） and a control group by random number table method, 40 cases in each group. The control group was treated by normal saline 100 mL with dexamethasone 10 mg enema, whilethe combined group was given Yiyi Fuzi Baijiang powder 100 mL （coix seed 30 g, aconitum carmichaeli debx 6 g, herba patriniae 15 g, radix paeoniae alba 15 g, frankincense 6 g, myrrh 6 g, glycyrrhiza uralensis 6 g） combined with dexamethasone 10 mg enema, one therapeutic course was 10 days, and after 3 courses, the clinical efficacy was observed in the two groups. The differences of erythrocyte sedimentation rate （ESR）, the number of red blood cell （RBC） and white blood cell （WBC） positive patients in stool routine were compared before and after treatment, and the clinical therapeutic effects were observed in the two groups.Results After treatment, the ESR was reduced in both groups compared to that before treatment, the numbers of RBC and WBC positive patients in stool routine were decreased in both group compared to those before treatment, and the degrees of changes were more significant in combined group than those in the control group [ESR （mm/1 h）： 15.00±3.07 vs. 20.55±3.87, the number of RBC positive patients： 7 cases vs. 21 cases, the number of WBC positive patients： 14 cases vs. 21 cases, allP 〈 0.05]. The total effective rate of combined group was significantly higher than that of the control group [92.5% （37/40） vs. 75.0% （30/40）,P 〈 0.05].Conclusion The clinical effect of Yiyi Fuzi Baijiang powder combined with dexamethasone enema was superior to
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2017年第4期419-422,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
国家中医药管理局科技支撑计划（2013BAI02B05）
关键词
薏苡附子败酱散
脾肾阳虚
溃疡性结肠炎
中西医结合结合疗法
Yiyi Fuzi Baijiang powder
Yang-deficiency of spleen and kidney
Ulcerative colitis
Combination of traditional Chinese and western medicine method
